Treatment for vaginal atrophy in post-menopausal women using CO2 laser
Official title: Efficacy of Fractional CO2 Laser Treatment in Post-Menopausal Women With Vaginal Atrophy
Run by Cairo University · NCT06726746 · Data updated 2026-11-12
This study is testing if a CO2 laser treatment can help relieve symptoms of vaginal atrophy in post-menopausal women.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 45 Years to 65 Years |
| Sex | Women only |
| Enrollment | 20 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | October 1, 2023 |
| Main results expected | March 1, 2025 |
| Study ends | March 1, 2025 |
| Registry record updated | December 10, 2024 |
| Trial ID | NCT06726746 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are sexually active post-menopausal women aged 45 to 65 experiencing symptoms of vaginal atrophy.
✕Probably not a fit
Patients with recent hormonal therapy, active infections, or serious chronic conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the efficacy of fractional CO2 laser treatment for alleviating symptoms of vaginal atrophy in post-menopausal women. It involves a prospective design with 30 participants who will attend four visits over a 12-week period. During the first three visits, participants will receive laser interventions, while the final visit will assess their satisfaction and any adverse events. The study will also evaluate changes in vaginal health and sexual function through standardized questionnaires and pelvic examinations.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the quality of life and sexual health for post-menopausal women suffering from vaginal atrophy.
How similar studies have gone: Other studies have shown promising results with laser treatments for similar conditions, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Menopausal women whose ages ranged from 45 to 65 years. 2. Sexually active 3. Had symptoms of VVA (vaginal dryness, irritation, soreness, or dyspareunia) Exclusion Criteria: 1. Any history of hormonal therapy within the past 6 months 2. Vaginal moisturizer or lubricant applications within the past 30 days 3. Acute/recurrent urinary tract infection 4. Active genital infection 5. Prolapse stage II or more based on examination 6. Psychiatric disorders 7. Undiagnosed vaginal bleeding 8. Any serious disease or chronic condition that could interfere with study compliance
Where it's running
-
Cairo University
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Daniel Onsi
- Email: daniel.onsi@ngu.edu.eg
- Phone: +201272755335
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.