Treatment for vaginal atrophy and related conditions using a novel gel dressing

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial focuses on treating vulvovaginal skin conditions such as vaginal atrophy, lichen sclerosus, and lichen planus in adult women using a new gel dressing. The study aims to evaluate both the short- and long-term safety and efficacy of this treatment. Participants will be monitored for their symptoms and overall recovery throughout the trial period. The study involves a series of assessments to determine the effectiveness of the gel in alleviating symptoms associated with these conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed atrophic vaginitis, lichen sclerosus, lichen simplex chronicus or lichen planus
* Continuous vulvovaginal symptoms
* Access to smartphone and tablet, laptop or computer
* Access to a valid email address

Exclusion Criteria:

* Unable to provide informed consent
* Patient unable to apply topical device
* Allergy or intolerance to ingredients or excipients of the formulation of studied products
* Systemic hormonal therapy started less than 30 days before baseline
* Systemic corticosteroids ongoing treatment or used within the last 30 days before baseline
* Ongoing topical HRT or corticosteroid treatment for the indication under investigation
* Topical HRT or corticosteroid treatment used for the indication under investigation within the last 30 days before baseline

Where it's running

• Cahaba Dermatology & Skin Health Center
  Birmingham, Alabama, United States Recruiting
• Velvet Clinical Research
  Burbank, California, United States Recruiting
• WR-PRI, LLC (Newport Beach)
  Newport Beach, California, United States Recruiting
• WR-Carolina Institute for Clinical Research
  Fayetteville, North Carolina, United States Recruiting
• Southern Urogynecology
  West Columbia, South Carolina, United States Recruiting
• WR-Global Medical Research, LLC
  Dallas, Texas, United States Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• F-GYN injection for vaginal dryness and vaginal/vestibular atrophy

  This study tests whether a one-time F-GYN injection can relieve vaginal dryness and related symptoms in adult women with atrophic vaginitis/vestibulovaginal atrophy compared with standard non-hormonal care.

  Recruiting at 3 sites Biovico Sp. z o.o. · Bolesławice and 2 other locations · NCT07701863

• Burden of vaginal and urinary menopause symptoms in breast cancer survivors

  This study will see how common and how severe genitourinary menopause symptoms are in breast cancer survivors receiving single-mode cancer treatment compared with controls.

  Recruiting Jessa Hospital · Hasselt, Limburg · NCT07563621

• Pixel CO2 (FemiLift) laser treatment for vulvo-vaginal atrophy

  This trial tests whether the Pixel CO2 (FemiLift) laser can relieve symptoms and restore healthier vaginal tissue in postmenopausal women with vulvo-vaginal atrophy.

  Recruiting Hillel Yaffe Medical Center · Hadera · NCT07024667

• Nonhormonal vulvovaginal gel to relieve menopausal vulvovaginal symptoms

  This will test a hormone-free vulvovaginal gel in postmenopausal women with genitourinary syndrome of menopause to see if it reduces vaginal atrophy symptoms and improves daily quality of life.

  Recruiting Mucosa Innovations, S.L. · Madrid, Madrid · NCT06962345

• Combining topical hyaluronic acid with high-concentration oxygen therapy for menopausal symptoms

  This study is testing if a treatment that combines a special gel and high-concentration oxygen can help postmenopausal women, including those who had breast cancer, feel better by reducing vaginal dryness and other symptoms.

  Recruiting Fondazione IRCCS Policlinico San Matteo di Pavia · Pavia, Pavia · NCT06879938

• Er:YAG laser plus vaginal estriol for menopausal genitourinary symptoms

  This trial will test whether adding Er:YAG laser treatment to low‑dose vaginal estriol helps postmenopausal women with genitourinary syndrome of menopause.

  Recruiting University of Nove de Julho · São Paulo, São Paulo · NCT06873971

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.