Treatment for rejuvenating skin around the eyes using a 1927 nm diode laser

An Open-Label, Single Center Clinical Study to Evaluate the Efficacy of Periorbital Rejuvenation With a 1927 nm Diode Laser Treatment

Not applicable Interventional National Taiwan University Hospital · NCT05811026

This study is testing a new laser treatment to see if it can improve the skin around the eyes for people looking to rejuvenate that area.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment20 (estimated)
Ages30 Years to 65 Years
SexAll
SponsorNational Taiwan University Hospital Academic / other
Locations1 site (Taipei)
Trial IDNCT05811026 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the efficacy and safety of a 1927 nm diode laser for rejuvenating the skin around the eyes. Participants will be randomized into two groups, receiving treatments at either a 2-week or 4-week interval using the Solta CLEAR+BRILLIANT Laser System. The study aims to assess the therapeutic effects of this laser treatment on periorbital skin, focusing on treatment design and outcomes. It is an open-label, single-center trial conducted at the National Taiwan University Hospital.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 30 to 65 years with no significant skin lesions or inflammation.

Not a fit: Patients with chronic skin diseases, recent facial treatments, or serious health conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a non-invasive option for improving the appearance of skin around the eyes.

How similar studies have performed: Other studies using laser treatments for skin rejuvenation have shown promising results, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. aged between 30 and 65 years old;
2. no significant skin lesions or inflammation on the facial skin;
3. willing and able to comply with study requirements, instructions, and restrictions;
4. signed informed consent form.

Exclusion Criteria:

1. underwent facial active treatment, such as using laser, intense pulsed light, radiofrequency skin tightening, ultrasound skin tightening, botulinum toxin, or dermal fillers injection, within the previous six months;
2. have chronic skin diseases such as atopic dermatitis, psoriasis, chronic urticaria, vitiligo, rosacea, or keloid;
3. pregnant or breastfeeding;
4. suffered from acute illnesses or infections requiring treatment within 14 days before entering the study;
5. have had serious illnesses (such as heart disease, lung disease, brain disease, or liver disease) within the previous three months;
6. allergic to Lidocaine or Prilocaine used in topical anesthetic cream or suffer from methemoglobinemia;
7. used any skin medication on the face within 30 days before the trial, deemed by the principal investigator to affect the study results;
8. deemed unsuitable for the study by the principal investigator.

Where this trial is running

Taipei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions LaserPeriorbital1927 nmperiorbital rejuvenation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.