Treatment for pudendal neuralgia using pulsed radiofrequency and ganglion impar block
Combined Pulsed Radiofrequency of the Pudendal Nerve With Ganglion Impar Block Effectively Alleviates Pudendal Neuralgia
This study is testing a new treatment that combines pulsed radiofrequency and a nerve block to see if it helps people with pudendal neuralgia feel less pain and improve their overall well-being.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Peking University People's Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Trial ID | NCT06461312 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of a combined treatment approach using pulsed radiofrequency of the pudendal nerve alongside a ganglion impar block for patients suffering from pudendal neuralgia. Participants will undergo a series of assessments before and after treatment, including pain levels and psychological factors such as anxiety and depression. The study aims to compare this combined method with traditional treatments to determine its efficacy and provide guidance for clinical practice.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 80 diagnosed with pudendal neuralgia who have not responded well to conservative treatments.
Not a fit: Patients with pain due to pelvic malignancies, autoimmune diseases, or those who have undergone pelvic surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly alleviate chronic pain and improve the quality of life for patients with pudendal neuralgia.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in using nerve blocks for pain management, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age between 18 and 80 years old; 2. Diagnosis of pudendal neuralgia meets the Nantes criteria. essential criteria include the following：1）Pain in the territory of the pudendal nerve；2） Pain is predominantly experienced while sitting；3) The pain does not wake the patient at night；4）Pain with no objective sensory impairment；5）Pain relieved by diagnostic pudendal nerve block； 3. Received conservative treatment for more than 3 months, and either had poor response to conservative treatment or intolerable medication side effects. 4. Capable of signing informed consent form. Exclusion Criteria: 1. Pain caused by pelvic malignant diseases or autoimmune diseases; 2. Pain caused by pelvic surgery; 3. Taking anticoagulant drugs or having abnormal coagulation function; 4. Pregnancy; 5. Systemic infectious diseases; 6. Inability to complete scale assessments.
Where this trial is running
Beijing, Beijing Municipality
- People's Hospital of Peking University — Beijing, Beijing Municipality, China (Recruiting)
Study contacts
- Principal investigator: Yiming Liu, MD — Peking University People's Hospital
- Study coordinator: Yifan Yang, MD
- Email: enayanyan0227@126.com
- Phone: 18701545165
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.