Treatment for pain caused by upper cluneal nerve entrapment

Treatment of Upper Cluneal Nerve Entrapment Syndrome for Reduction of Low Back Pain: Single-arm Experimental Study

NA · Istituto Ortopedico Rizzoli · NCT06059612

This study is testing a new way to treat low back pain caused by a trapped nerve by giving injections to help relieve the pain for people who haven't found relief with regular treatments.

Quick facts

PhaseNA
Study typeInterventional
Enrollment78 (estimated)
Ages18 Years and up
SexAll
SponsorIstituto Ortopedico Rizzoli (other)
Locations1 site (Bologna)
Trial IDNCT06059612 on ClinicalTrials.gov

What this trial studies

This study focuses on treating superior cluneal nerve entrapment syndrome, a condition that causes low back pain due to nerve compression. The approach involves identifying trigger points on the posterior iliac crest and administering injections to alleviate pain. The study aims to provide effective treatment options for patients suffering from low back pain that has not been resolved through traditional methods. It highlights the importance of recognizing this syndrome, which is often overlooked in the diagnosis of lumbosacral spine disorders.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 99 who exhibit positive trigger points for the superior cluneal nerve.

Not a fit: Patients with urgent criteria for spinal surgery or those with negative trigger point evaluations will not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly reduce low back pain for patients suffering from this specific nerve entrapment.

How similar studies have performed: While this specific approach may be novel in Italy, similar interventions for nerve entrapment syndromes have shown success in other studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients with age between 18 and 99 years
* male and female sex
* superior cluneal nerve trigger point positivity at clinical evaluation
* absence of urgent criteria for spinal surgery

Exclusion Criteria:

* patients younger than 18 years old
* patients who have not given consent to be included in the study
* patients with negative upper cluneal nerve trigger point - emergency criteria for spine surgery
* pregnant women - patients allergic to local anesthetic
* patients with language barrier

Where this trial is running

Bologna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Superior Cluneal Nerve Entrapment, Superior cluneal nerve, nerve entrapment

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.