Treatment for Oral Lichen Planus using Paeoniflorin and Light Therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to treat Oral Lichen Planus (OLP), a chronic inflammatory condition of the oral mucosa, using a combination of paeoniflorin, a compound from traditional Chinese medicine, and photodynamic therapy. The study will categorize patients based on TCM differentiation and conduct a randomized controlled trial to evaluate the effectiveness of this combined treatment approach. By targeting the underlying autoimmune mechanisms and utilizing innovative therapies, the study seeks to improve patient outcomes and enhance understanding of treatment mechanisms for OLP.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients with oral lichen planus
* male or female patients older than 18 years of age
* patients willing to participate with signed informed consent.

Exclusion Criteria:

* pregnant or lactating
* had serious systemic diseases of the heart, lung, liver, and kidney, or had tumors
* were unwilling to participate in the experiment.

Where it's running

• Peking University Third Hospital
  Beijing, China Recruiting

Study contacts

• Principal investigator: Zhihui Zhang — Peking University Third Hospital
• Study coordinator: Zhihui Zhang, Dr.
• Email: wisdomzhangzhihui@163.com
• Phone: 010-82266125

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Topical bromelain versus topical corticosteroid for oral lichen planus

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.