Treatment for moderate to severe allergic rhinitis using electroacupuncture and microneedle knife
A Clinical Randomized Controlled Study of Electroacupuncture Combined With Microneedle Knife in the Treatment of Moderate to Severe Allergic Rhinitis
This study is testing if a new treatment that combines electroacupuncture and a microneedle knife can help people with moderate to severe allergic rhinitis feel better compared to standard medications.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Zhejiang Hospital Academic / other |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT06890260 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of electroacupuncture combined with a microneedle knife in treating moderate to severe allergic rhinitis. Patients who meet specific inclusion criteria will be randomly assigned to either the treatment group or a control group receiving standard medications. The primary outcome will be measured using the total nasal symptom score, while secondary outcomes will include various serum markers and quality of life assessments. Follow-up assessments will occur at multiple intervals to monitor treatment efficacy over time.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 75 with a clinical diagnosis of moderate to severe allergic rhinitis who have not used antihistamines or nasal steroids in the past month.
Not a fit: Patients with other forms of rhinitis, serious comorbid conditions, or those who are pregnant or lactating may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a non-pharmacological alternative for patients suffering from allergic rhinitis.
How similar studies have performed: While the combination of electroacupuncture and microneedle knife is a novel approach, similar studies have shown promising results with acupuncture in treating allergic conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Those with clinical and laboratory diagnosis of moderate to severe allergic rhinitis; 2. Aged ≥18 years and ≤75 years, with no restriction on gender or ethnicity; 3. Not taking drugs such as antihistamines or nasal steroids within 1 month before enrollment; 4. Those who voluntarily participated in this study and signed an informed consent form, and who were able to adhere to outpatient treatment for 4 weeks. Exclusion Criteria: 1. Atrophic rhinitis, hypertrophic rhinitis, vasomotor rhinitis, acute and chronic sinusitis, nasal polyps, severe septal deviation, eosinophilia non-allergic rhinitis; 2. Those with other allergic diseases such as asthma, urticaria, and colds that cause nasal congestion, runny nose, and sneezing; 3. Those who have serious diseases such as cardiovascular, cerebrovascular, hepatic, renal and hematopoietic systems in combination; 4. Pregnant or lactating women, psychiatric patients, patients with malignant tumors.
Where this trial is running
Hangzhou, Zhejiang
- Zhejiang Hospital — Hangzhou, Zhejiang, China (Recruiting)
Study contacts
- Study coordinator: Pengfei Qiu
- Email: 764360784@qq.com
- Phone: +8618158508449
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.