Treatment for moderate to severe allergic rhinitis using electroacupuncture and microneedle knife

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of electroacupuncture combined with a microneedle knife in treating moderate to severe allergic rhinitis. Patients who meet specific inclusion criteria will be randomly assigned to either the treatment group or a control group receiving standard medications. The primary outcome will be measured using the total nasal symptom score, while secondary outcomes will include various serum markers and quality of life assessments. Follow-up assessments will occur at multiple intervals to monitor treatment efficacy over time.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Those with clinical and laboratory diagnosis of moderate to severe allergic rhinitis;
2. Aged ≥18 years and ≤75 years, with no restriction on gender or ethnicity;
3. Not taking drugs such as antihistamines or nasal steroids within 1 month before enrollment;
4. Those who voluntarily participated in this study and signed an informed consent form, and who were able to adhere to outpatient treatment for 4 weeks.

Exclusion Criteria:

1. Atrophic rhinitis, hypertrophic rhinitis, vasomotor rhinitis, acute and chronic sinusitis, nasal polyps, severe septal deviation, eosinophilia non-allergic rhinitis;
2. Those with other allergic diseases such as asthma, urticaria, and colds that cause nasal congestion, runny nose, and sneezing;
3. Those who have serious diseases such as cardiovascular, cerebrovascular, hepatic, renal and hematopoietic systems in combination;
4. Pregnant or lactating women, psychiatric patients, patients with malignant tumors.

Where it's running

• Zhejiang Hospital
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: Pengfei Qiu
• Email: 764360784@qq.com
• Phone: +8618158508449

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.