Treatment for coronary artery disease using drug-coated balloons

Drug-coating Balloon Treatment in Coronary Artery Disease: a Prospective, Multicenter, Registry Study (ULTIMATE-DCB)

Observational Nanjing First Hospital, Nanjing Medical University · NCT04255563

This study is testing how well drug-coated balloons work for treating people with coronary artery disease and checking if they are safe to use.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
Ages18 Years and up
SexAll
SponsorNanjing First Hospital, Nanjing Medical University Academic / other
Locations1 site (Nanjing, Jiangsu)
Trial IDNCT04255563 on ClinicalTrials.gov

What this trial studies

This observational study investigates the efficacy and safety of drug-coated balloon (DCB) treatment in patients with coronary artery disease (CAD). It is a prospective, multi-center registry that enrolls patients undergoing DCB treatment without strict inclusion and exclusion criteria. Data and images will be collected during the procedure and at follow-up visits to assess outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with coronary artery disease who are suitable for drug-coated balloon treatment.

Not a fit: Patients who are pregnant, have contraindications to contrast media or antiplatelet therapy, or are in cardiac shock may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a less invasive option for managing coronary artery disease, potentially improving patient outcomes.

How similar studies have performed: Other studies have shown promising results with drug-coated balloon treatments in similar patient populations, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients suitable for DCB treatment

Exclusion Criteria:

* Pregnancy
* Contraindications to contrast media, antiplatelet therapy, or paclitaxel
* Expected life less than 12 months
* Cardiac shock

Where this trial is running

Nanjing, Jiangsu

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Coronary Artery Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.