Treatment for atrophic acne scars using injections
Efficacy of Intralesional Injection of Pentoxifylline, Platelet-Rich Plasma, and Combined
This study is testing whether injections of pentoxifylline, platelet-rich plasma, or a mix of both can help people with atrophic acne scars look better and feel more confident.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06319768 on ClinicalTrials.gov |
What this trial studies
This study evaluates the efficacy of intralesional injections of pentoxifylline, platelet-rich plasma (PRP), and a combination of both in patients suffering from atrophic acne scars. Atrophic acne scars are a common and persistent complication of acne, which can significantly impact a patient's psychological well-being. The study aims to determine which treatment approach is most effective in reducing the appearance of these scars. Participants will be assessed based on their age, sex, and type of atrophic scars, while those with certain medical conditions will be excluded from participation.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals over 18 years old with any type of atrophic acne scars.
Not a fit: Patients who are pregnant, have coagulation disorders, skin infections, hormonal disturbances, chronic diseases, or refuse to participate may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the appearance of atrophic acne scars, enhancing patients' quality of life.
How similar studies have performed: While the combination of pentoxifylline and PRP is a relatively novel approach, similar studies have shown promising results with PRP in treating various types of scars.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged \> 18 years old. * Both sexes. * All types of atrophic acne scars Exclusion Criteria: * • Pregnant or lactating women. * Coagulation disorders or anemia. * Skin infections. * Patients with hormonal disturbance. * Chronic disease e.g: diabetes, renal disease....etc. * Refusal to participate.
Where this trial is running
Sohag
- Sohag university Hospital — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: MARIAM M SOLIMAN, resident
- Email: mariam-mosaad-post@med.sohag.edu.eg
- Phone: 01151180969
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.