Treatment for abnormal uterine bleeding in women
Randomized Trial of Mefenamic Acid Versus Tranexamic Acid in Management of Abnormal Uterine Bleeding
This study is testing if mefenamic acid can help women with abnormal uterine bleeding feel better and manage their symptoms.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 130 (estimated) |
| Ages | 15 Years to 45 Years |
| Sex | Female |
| Sponsor | Egymedicalpedia Industry-sponsored |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06369012 on ClinicalTrials.gov |
What this trial studies
This study focuses on managing abnormal uterine bleeding (AUB), a common issue among reproductive-age women that can lead to significant health complications such as anemia. It aims to evaluate the effectiveness of mefenamic acid in treating AUB, particularly in women diagnosed with uterine cavity lesions or bleeding tendencies. The study utilizes non-invasive imaging techniques, such as ultrasonography, to assess uterine pathologies and determine the appropriate treatment approach. By improving the management of AUB, the study seeks to enhance the quality of life for affected women.
Who should consider this trial
Good fit: Ideal candidates for this study are females aged 15-45 who experience abnormal uterine bleeding due to endometrial or uterine cavity lesions.
Not a fit: Patients with renal or hepatic impairment, previous thromboembolic disease, or those taking medications that cause AUB may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce the incidence of anemia and related complications in women suffering from abnormal uterine bleeding.
How similar studies have performed: Other studies have shown success in managing abnormal uterine bleeding with similar non-invasive approaches, indicating a promising avenue for treatment.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any female patient in Child bearing period aging from 15-45 years complaining of Abnormal uterine. * Abnormal uterine bleeding due to endometrial, uterine cavity lesions as diagnosed by TVS or bleeding tendency e.g. Thrombocytopenia, Platelets dysfunction and coagulation defects Exclusion Criteria: * Personal history of renal or hepatic impairment; previous thromboembolic disease, peptic ulcer. * Females with evident drugs intake that cause AUB e.g warfarin, low molecular weight heparin. * Vaginal, vulvar, and cervical causes of bleeding. * Bleeding on top of Use of hormonal and non-hormonal contraception.
Where this trial is running
Cairo
- Ain Shams University Hospitals — Cairo, Egypt (Recruiting)
Study contacts
- Principal investigator: Omnia Bakar Bakar, Lecturer — Obstetrics and Gynecology, Faculty of Medicine, Ain Shams University
- Study coordinator: Rania Gamal Anwar, M.D
- Email: dr.raniagamal2015@yahoo.com
- Phone: +201283262383
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.