Treatment approach for perforated diverticulitis using a damage control strategy
The Damage Control Strategy for the Treatment of Perforated Diverticulitis of the Sigmoid Colon With Diffuse Peritonitis - a Retrospective, Multicenter, Transnational Cohort Study
Städtisches Klinikum München GmbH · NCT04220840
This study is testing a two-step surgery approach for treating perforated diverticulitis to see if it can lower the chances of needing a colostomy bag while still being safe for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Sex | All |
| Sponsor | Städtisches Klinikum München GmbH (other) |
| Locations | 1 site (Munich, Bavaria) |
| Trial ID | NCT04220840 on ClinicalTrials.gov |
What this trial studies
This study evaluates the damage control strategy for treating perforated diverticulitis of the sigmoid colon with diffuse peritonitis. The approach involves a two-stage surgical procedure: an initial emergency surgery that includes limited resection and temporary closure, followed by a second look surgery 48-72 hours later for definitive reconstruction. The goal is to determine if this strategy can reduce the stoma rate while maintaining safety comparable to other surgical methods. Data from patients undergoing this procedure will be collected and analyzed to assess outcomes.
Who should consider this trial
Good fit: Ideal candidates are patients who have undergone surgery for perforated diverticulitis with generalized peritonitis.
Not a fit: Patients with incomplete data sets will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly lower the need for permanent stomas in patients with perforated diverticulitis.
How similar studies have performed: While the damage control strategy is a recognized approach, its specific application in this context is still under evaluation, making this a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: all patients who were operated for perforated diverticulitis with generalized peritonitis Exclusion Criteria: incomplete data sets
Where this trial is running
Munich, Bavaria
- Dr. Maximilian Sohn — Munich, Bavaria, Germany (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Perforated Diverticulitis