Transperineal laser treatment for prostate cancer

Transperineal Laser Ablation Treatment for Prostate Cancer Registry: a Retrospective and Multicenter Evaluation

Observational Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT05163197

This study is looking at how safe and effective a new laser treatment for localized prostate cancer is, by gathering information from patients who have tried it.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexMale
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Academic / other
Locations1 site (Amsterdam)
Trial IDNCT05163197 on ClinicalTrials.gov

What this trial studies

This observational registry collects data on the safety and feasibility of transperineal laser ablation (TPLA) for treating localized prostate cancer. The study aims to evaluate functional and oncological outcomes while determining baseline patient characteristics in a multicenter cohort. By analyzing data from patients who have undergone TPLA, the registry seeks to provide insights into the long-term effectiveness of this minimally invasive focal therapy compared to standard radical treatments.

Who should consider this trial

Good fit: Ideal candidates for this study are males with histologically confirmed localized prostate cancer who have undergone TPLA treatment.

Not a fit: Patients under 18 years old will not benefit from this study as they do not meet the eligibility criteria.

Why it matters

Potential benefit: If successful, this approach could offer a safer and more effective treatment option for prostate cancer, potentially preserving patients' quality of life.

How similar studies have performed: While pilot studies have shown TPLA to be safe and feasible, the long-term outcomes remain largely unknown, indicating this is a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male, histological-confirmed disease of localized prostate cancer, TPLA treatment for PCa is performed

Exclusion Criteria:

* Age \< 18 years

Where this trial is running

Amsterdam

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Prostate CancerLaser AblationMinimal invasiveFocal therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.