Transcutaneous phrenic nerve stimulation to prevent diaphragm atrophy in ICU patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the effects of transcutaneous phrenic nerve stimulation on preventing diaphragm atrophy in patients requiring invasive mechanical ventilation for over 72 hours. Participants will receive electrical stimulation through the skin to contract the diaphragm muscle, with the aim of enhancing muscle function and facilitating earlier extubation. The study will evaluate diaphragm muscle condition using ultrasonography and collect various patient data during the intervention period. Conducted at a single center, the study aims to enroll a total of 80 patients over the course of one year.

Why it matters

Who can join: the full rules

Inclusion Criteria:Patients on invasive mechanical ventilation for 72 hours or more Patients older than 18 years

Exclusion Criteria: Patients under 18 years of age

* Patients with less than 72 hours of mechanical ventilation
* Pregnancy
* Patients with a body mass index above 35kg/m²
* Neuromuscular disease
* Refractory epilepsy
* Patients with pacemakers
* ARDS
* Unilateral or bilateral diaphragm paralysis
* Presence of pneumothorax
* Patients with large right pleural effusion
* Tracheostomized patients
* Patients undergoing upper abdominal surgery

Where it's running

• Dr.SadiKonuk EAH
  Istanbul, Bakirkoy, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Safiye Tuba Kaplan
• Email: sipahituba79@gmail.com
• Phone: +9

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Deciphering why some patients stay a long time in the ICU using detailed clinical profiling

  This study will try to identify clinical patterns in adults who stay in the ICU five days or longer to better understand persistent critical illness.

  Recruiting at 6 sites Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa · Lisbon, Lisbon District and 6 other locations · NCT07510776

• Delphi consensus to guide mechanical insufflation-exsufflation use in the ICU

  A panel of ICU and lung specialists will use a structured survey process to agree on best practices for using mechanical insufflation-exsufflation to help airway clearance in critically ill patients.

  Recruiting at 4 sites Medipol University · Naples and 3 other locations · NCT07420946

• Behavioral health collaborative care for family members of ICU survivors in the Post-ICU clinic pilot

  This pilot tests a telehealth-based behavioral health program using the NeuroFlow app for family members of ICU survivors to try to reduce anxiety, depression, and PTSD symptoms.

  Recruiting Medical University of South Carolina · Charleston, South Carolina · NCT07390786

• When and how much fluid to remove in critically ill patients

  This study will test which patients, timing, and rates of fluid removal (diuretics or ultrafiltration) work best for critically ill adults in the ICU who need deresuscitation.

  Recruiting at 2 sites Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam and 1 other locations · NCT07275658

• Communication support for ventilated intensive care patients

  This project will try an eye-tracking tablet (JIB-Tours care) to help conscious, ventilated adults in ICU who cannot speak communicate with caregivers and family.

  Recruiting University Hospital, Tours · Le Mans and 2 other locations · NCT07251530

• Lowering sodium and chloride in diluent and maintenance IV fluids for critically ill adults

  This trial will try using salt-free glucose for medication dilutions and a low-salt maintenance fluid to see if lowering sodium and chloride helps adults who need a prolonged stay in the ICU.

  Recruiting Phase 4 University Hospital, Antwerp · Antwerp and 3 other locations · NCT07189091

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.