Transcranial stimulation for sudden deafness with tinnitus
The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus
This study is testing whether a type of brain stimulation can help people with sudden deafness and tinnitus feel better and improve their hearing.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 86 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT05964725 on ClinicalTrials.gov |
What this trial studies
This clinical study investigates the effects of transcranial direct current stimulation (tDCS) on patients suffering from sudden deafness accompanied by tinnitus. It is a prospective, single-center, randomized, controlled, double-blind trial involving 86 participants who will receive either tDCS or sham stimulation alongside traditional medical therapy. The study aims to evaluate the efficacy of tDCS in improving tinnitus symptoms and hearing recovery over a treatment period of 5 days, with follow-up assessments at 1, 3, and 6 months post-treatment. Various subjective scales will be used to measure changes in tinnitus severity and related symptoms.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-60 with sudden deafness and tinnitus lasting less than one month who have not received prior drug treatment.
Not a fit: Patients with conductive deafness, history of middle ear surgery, or those with tinnitus caused by specific conditions like Meniere disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a novel non-invasive option for patients suffering from sudden deafness and tinnitus.
How similar studies have performed: While the use of tDCS in treating tinnitus is an emerging area, similar studies have shown promising results, suggesting potential efficacy.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with tinnitus as the main complaint: patients subjectively feel sound in the ear or deep part of the head without internal or external sound stimulation, with or without hearing loss, and seek medical treatment * Patients with sudden deafness with tinnitus whose course is less than 1 month and have not received any drug treatment * Age 18-60 years * Tinnitus frequency is 125-8000 Hz Exclusion Criteria: * Patients with conductive deafness, history of middle ear surgery, pulsatile tinnitus caused by vascular aberration and tinnitus cause by Meniere disease * History of head trauma, central nervous system disease, mental disease, and drug abuse
Where this trial is running
Guangzhou, Guangdong
- Sun Yat-sen Memorial Hospital — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Principal investigator: Yuexin Cai, Doctor — Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- Study coordinator: Yuexin Cai, Doctor
- Email: panada810456@126.com
- Phone: +8613825063663
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.