Transcranial plasma stimulation for treating chronic insomnia

Study on the Therapeutic Effect and Mechanism of Transcranial Plasma Stimulation in the Treatment of Chronic Insomnia

Not applicable Interventional The First Hospital of Hebei Medical University · NCT06252779

This study is testing whether a new treatment called transcranial plasma stimulation can help people with chronic insomnia sleep better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorThe First Hospital of Hebei Medical University Academic / other
Locations1 site (Shijiazhuang)
Trial IDNCT06252779 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of transcranial plasma stimulation in treating chronic insomnia disorder. Conducted at the First Hospital of Hebei Medical University, it aims to enroll 40 patients aged 18-75 who meet specific criteria. The study will assess various scales, including the Hamilton Anxiety Scale and Pittsburgh Sleep Quality Index, before and after the intervention. The research will utilize advanced imaging techniques like TMS-EEG and functional MRI to explore the underlying mechanisms of the treatment.

Who should consider this trial

Good fit: Ideal candidates are right-handed adults aged 18-75 with chronic insomnia who have not responded well to sleep-improving medications.

Not a fit: Patients with severe mental illnesses, substance abuse issues, or unstable organic diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could significantly improve sleep quality and overall well-being for patients suffering from chronic insomnia.

How similar studies have performed: While the approach of using plasma stimulation is relatively novel, similar studies using transcranial stimulation techniques have shown promising results in treating various neurological conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age 18-75 years old, gender is not limited;
2. right-handed;
3. the audiovisual level is sufficient to complete the examinations required for the study;
4. No medication for 1 month before enrollment, or stable taking sleep-improving drugs but poor treatment effect;
5. Informed consent signed by the patient or family member.

Exclusion Criteria:

1. Substance abuse/dependence within 6 months prior to enrollment;
2. Have had other mental illnesses within 6 months prior to enrollment;
3. Those with severe or unstable organic diseases;
4. pregnant or lactating women;
5. Those with a score of 3 (suicide) in 17 items of the Hamilton Depression Rating Scale ≥ 3;
6. Those who have participated in any other clinical trials within 1 month before enrollment;
7. In the opinion of the investigator, there is a situation that is not suitable to participate in this study.

Where this trial is running

Shijiazhuang

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Insomnia Disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.