Transcranial direct current stimulation for people with subthreshold depression

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of multi-session transcranial direct current stimulation (tDCS) on loneliness, mood, and depressive symptoms in individuals experiencing subthreshold depression. Participants will be divided into three groups: a personalized tDCS group, a conventional tDCS group, and a sham control group. Each participant will undergo 10 sessions of tDCS, with assessments of their depression symptoms, loneliness, and mood conducted before, immediately after, and three months post-intervention. Functional MRI scans will also be performed to assess brain activity and connectivity related to the treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* No histories of learning impairment, major psychiatric disorders including Major Depressive Disorder or neurological disorders
* At least primary school education
* Subthreshold depression

Exclusion Criteria:

* On medication or treatments within 2 weeks prior to the beginning of the study that would affect the individual's brain, cognitive and affective functions

Where it's running

• The Education University of Hong Kong
  Hong Kong, Hong Kong Recruiting

Study contacts

• Principal investigator: Nichol ML Wong, PhD — Education University of Hong Kong
• Study coordinator: Nichol ML Wong, PhD
• Email: nmlwong@eduhk.hk
• Phone: 852-29487431

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using tDCS to improve emotional health in young adults with mild depressive symptoms

  This study will test whether transcranial direct current stimulation (tDCS) can improve mood, motivation, and emotion regulation in 18–35-year-olds with subthreshold depression.

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• Online skills training to improve emotion regulation and relationships for adults with childhood adversity and mild depression

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  This project will test whether coaching-style behavioral activation delivered by trained lay counselors over phone or video can prevent depression in low-income older adults who recently had a first stroke and currently have mild or no depressive symptoms.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT06864715

• Using brain stimulation to help young people with mild depression

  This study is testing if a type of brain stimulation can help young people aged 12-25 with mild depression feel better.

  Recruiting Guangzhou Psychiatric Hospital · Guangzhou, Guangdong · NCT06294184

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.