Transcranial direct current stimulation for people with subthreshold depression
Personalised Transcranial Direct Current Stimulation to Reduce Daily Loneliness in People With Subthreshold Depression
NA · Education University of Hong Kong · NCT06517121
This study is testing whether a special brain stimulation treatment can help people with mild depression feel less lonely and improve their mood.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 204 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Education University of Hong Kong (other) |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT06517121 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of multi-session transcranial direct current stimulation (tDCS) on loneliness, mood, and depressive symptoms in individuals experiencing subthreshold depression. Participants will be divided into three groups: a personalized tDCS group, a conventional tDCS group, and a sham control group. Each participant will undergo 10 sessions of tDCS, with assessments of their depression symptoms, loneliness, and mood conducted before, immediately after, and three months post-intervention. Functional MRI scans will also be performed to assess brain activity and connectivity related to the treatment.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with subthreshold depression who do not have major psychiatric or neurological disorders.
Not a fit: Patients with major depressive disorder or those currently on medication affecting brain function may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a novel non-invasive treatment option for individuals suffering from subthreshold depression.
How similar studies have performed: Previous studies have shown promising results with tDCS in treating various forms of depression, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * No histories of learning impairment, major psychiatric disorders including Major Depressive Disorder or neurological disorders * At least primary school education * Subthreshold depression Exclusion Criteria: * On medication or treatments within 2 weeks prior to the beginning of the study that would affect the individual's brain, cognitive and affective functions
Where this trial is running
Hong Kong
- The Education University of Hong Kong — Hong Kong, Hong Kong (RECRUITING)
Study contacts
- Principal investigator: Nichol ML Wong, PhD — Education University of Hong Kong
- Study coordinator: Nichol ML Wong, PhD
- Email: nmlwong@eduhk.hk
- Phone: 852-29487431
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Subthreshold Depression