Transcranial alternating current stimulation for cognitive issues in methamphetamine users
tACS Treatment for Cognitive Impairments in Methamphetamine Addicts
This study is testing if a brain stimulation technique can help improve thinking skills in people struggling with methamphetamine use.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 300 (estimated) |
| Ages | 18 Years to 55 Years |
| Sex | All |
| Sponsor | Beijing HuiLongGuan Hospital Academic / other |
| Locations | 1 site (Mianyang) |
| Trial ID | NCT06292156 on ClinicalTrials.gov |
What this trial studies
This study evaluates cognitive function in patients with methamphetamine use disorder and investigates the underlying pathological mechanisms using EEG and biological assessments. It examines the effects of transcranial alternating current stimulation (tACS) on cognitive impairments, comparing a theta treatment group, an alpha active control group, and a sham control group. The goal is to determine whether tACS can improve cognitive function in this population.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with methamphetamine use disorder who do not have co-occurring substance use or serious physical or mental health conditions.
Not a fit: Patients with serious physical illnesses, cranial defects, or those currently undergoing medical treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could enhance cognitive function and overall quality of life for individuals recovering from methamphetamine addiction.
How similar studies have performed: While there is limited research specifically on tACS for methamphetamine-related cognitive impairments, similar approaches using tACS for other cognitive disorders have shown promise.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis diagnosis of methamphetamine use disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) * None of participants had mixed use of other drugs * None of participants had physical disability * None of participants had acute physical or mental illness, hallucinations, acute withdrawal symptoms * None of participants were receiving any medical treatment Exclusion Criteria: * Intracranial hypertension * Cranial defects * Tumors * Serious physical illnesses (e.g., cardiovascular, liver, kidney, gastrointestinal disorders) * Infectious diseases * Immune system disorders
Where this trial is running
Mianyang
- Xin Hua Drug Rehabilitation Center — Mianyang, China (Recruiting)
Study contacts
- Study coordinator: Xiangyang Zhang, M.D.,Ph.D
- Email: zhangxy@psych.ac.cn
- Phone: +86-10-62710644
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.