Training to prevent falls in people with Alzheimer's disease
Official title: Motor Learning of Fall Resistant Skills From Laboratory-induced Falling Among People With Mild Alzheimer's Disease
Run by Georgia State University · NCT05205980 · Data updated 2026-11-12
This study tests if people with mild Alzheimer's can learn skills on a treadmill to help prevent falls in their daily lives.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 65 Years to 90 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Georgia State University Academic / other |
| Locations | 1 site (Valdosta, Georgia) |
| Status | Recruiting |
| Started | April 28, 2023 |
| Main results expected | October 30, 2026 |
| Study ends | October 30, 2026 |
| Registry record updated | February 4, 2026 |
| Trial ID | NCT05205980 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 65 and older with a clinical diagnosis of probable Alzheimer's disease who can walk independently.
✕Probably not a fit
Patients with a history of perturbation training, uncontrolled hypertension, osteoporosis, or other significant neurological or psychiatric conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study examines whether individuals with mild Alzheimer's disease can learn skills to prevent falls through perturbation training on a treadmill. Participants will be divided into two groups: one receiving the training and the other not. Both groups will be exposed to perturbations on the ground immediately after training and again three or six months later. The study will track falls in daily living over six months to assess the effectiveness of the training in improving fall resistance. The research aims to determine if participants can adapt to and retain these skills in various contexts.
Why it matters
Potential benefit: If successful, this training could significantly reduce the risk of falls and related injuries in patients with Alzheimer's disease.
How similar studies have gone: While similar approaches have been explored, this specific application of perturbation training in Alzheimer's patients is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants must be at least 65 years old; * Participants have a clinical diagnosis of probable AD; * Participants can read and understand English; * Participants must be able to walk independently at least 25 feet; * Participants must be able to stand independently for at least 30 seconds; * Participants must have a Montreal Cognitive Assessment score of 11-21 or Mini Mental Status Examination score between 18 and 23. Exclusion Criteria: * Individuals have ever experienced perturbation training; * Individuals have hypotension or uncontrolled hypertension; * Individuals exhibit osteoporosis; * Participants suffer from coexisting psychiatric disorders, or other neurological conditions, or injuries, etc.
Where it's running
-
Reminiscent
Valdosta, Georgia, United States Recruiting
Study contacts
- Principal investigator: Feng Yang, PhD — Georgia State University
- Study coordinator: Feng Yang, PhD
- Email: fyang@gsu.edu
- Phone: 404-413-8357
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.