Clinical trial Recruiting at 1 site Interventional Ages 65 to 90

Training to prevent falls in people with Alzheimer's disease

Official title: Motor Learning of Fall Resistant Skills From Laboratory-induced Falling Among People With Mild Alzheimer's Disease

Run by Georgia State University · NCT05205980 · Data updated 2026-11-12

This study tests if people with mild Alzheimer's can learn skills on a treadmill to help prevent falls in their daily lives.

More Alzheimer Disease trials

Quick facts

Study typeInterventional
Ages65 Years to 90 Years
SexAll
Enrollment30 (estimated)
SponsorGeorgia State University
Academic / other
Locations1 site (Valdosta, Georgia)
StatusRecruiting
StartedApril 28, 2023
Main results expectedOctober 30, 2026
Study endsOctober 30, 2026
Registry record updatedFebruary 4, 2026
Trial IDNCT05205980 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 65 and older with a clinical diagnosis of probable Alzheimer's disease who can walk independently.

Probably not a fit

Patients with a history of perturbation training, uncontrolled hypertension, osteoporosis, or other significant neurological or psychiatric conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines whether individuals with mild Alzheimer's disease can learn skills to prevent falls through perturbation training on a treadmill. Participants will be divided into two groups: one receiving the training and the other not. Both groups will be exposed to perturbations on the ground immediately after training and again three or six months later. The study will track falls in daily living over six months to assess the effectiveness of the training in improving fall resistance. The research aims to determine if participants can adapt to and retain these skills in various contexts.

Why it matters

Potential benefit: If successful, this training could significantly reduce the risk of falls and related injuries in patients with Alzheimer's disease.

How similar studies have gone: While similar approaches have been explored, this specific application of perturbation training in Alzheimer's patients is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants must be at least 65 years old;
* Participants have a clinical diagnosis of probable AD;
* Participants can read and understand English;
* Participants must be able to walk independently at least 25 feet;
* Participants must be able to stand independently for at least 30 seconds;
* Participants must have a Montreal Cognitive Assessment score of 11-21 or Mini Mental Status Examination score between 18 and 23.

Exclusion Criteria:

* Individuals have ever experienced perturbation training;
* Individuals have hypotension or uncontrolled hypertension;
* Individuals exhibit osteoporosis;
* Participants suffer from coexisting psychiatric disorders, or other neurological conditions, or injuries, etc.

Where it's running

  • Reminiscent
    Valdosta, Georgia, United States
    Recruiting

Study contacts

  • Principal investigator: Feng Yang, PhD — Georgia State University
  • Study coordinator: Feng Yang, PhD
  • Email: fyang@gsu.edu
  • Phone: 404-413-8357

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.