Training to improve working memory in adolescents with ADHD

Behavioral and Neural Target Engagement for ADHD Executive Working Memory Training

Not applicable Interventional Hartford Hospital · NCT06446284

This study is testing if a special memory training program can help improve brain function and reduce symptoms in teenagers with ADHD.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment130 (estimated)
Ages12 Years to 18 Years
SexAll
SponsorHartford Hospital Academic / other
Locations1 site (Hartford, Connecticut)
Trial IDNCT06446284 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to replicate previous findings on brain engagement in adolescents diagnosed with ADHD by assessing the effects of executive working memory (EWM) training. The study will involve 130 adolescents, with 90 diagnosed with ADHD and 40 as non-ADHD controls. Participants in the ADHD group will be randomly assigned to either a placebo training or an active EWM training program conducted remotely at home, with increasing difficulty over five weeks. The goal is to establish a link between brain activity changes and improvements in ADHD symptoms.

Who should consider this trial

Good fit: Ideal candidates for this study are adolescents aged 12-18 who have a diagnosis of ADHD and meet specific cognitive and language criteria.

Not a fit: Patients with comorbid psychiatric disorders or neurological conditions, as well as those with certain physical limitations, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to effective cognitive training interventions that significantly improve working memory and reduce ADHD symptoms in adolescents.

How similar studies have performed: Previous studies have shown promise in using cognitive training to improve ADHD symptoms, making this approach both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteriia:

* Diagnosis of ADHD
* English speaking
* Right-handed
* \>5th grade reading level
* \>80 IQ level

Exclusion Criteria:

* Braces, metal or implant devices
* Brain abnormality, neurological disorder
* TBI or loss of consciousness\>30 minutes
* Diagnosis of Psychosis, Bipolar Disorder, ASD, PTSD, OCD, SUD, Tourette's Disorder

Where this trial is running

Hartford, Connecticut

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions ADHD
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.