Training to improve walking balance after a stroke

Proactive and Reactive Perturbation Training to Reduce Falls and Improve Gait Stability in People with Chronic Stroke

NA · Medical University of South Carolina · NCT04855032

This study tests two different training methods to see if they can help people who have had a stroke improve their walking balance and reduce the risk of falling.

Quick facts

PhaseNA
Study typeInterventional
Enrollment86 (estimated)
Ages21 Years and up
SexAll
SponsorMedical University of South Carolina (other)
Locations1 site (Charleston, South Carolina)
Trial IDNCT04855032 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of two different methods of delivering mechanical perturbations during walking to improve balance and reduce the risk of falls in individuals who have experienced a stroke. Participants will engage in reactive and proactive perturbation training to assess their impact on post-stroke walking stability. The study aims to address the high incidence of falls among stroke survivors, which significantly affects their quality of life. By focusing on practical interventions, the research seeks to provide a solution to a prevalent issue in stroke rehabilitation.

Who should consider this trial

Good fit: Ideal candidates are individuals who have had a stroke at least 6 months prior and have experienced a fall or fear of falling.

Not a fit: Patients with severe neurological disorders, significant cardiovascular issues, or those with orthopedic conditions affecting gait may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance walking balance and reduce fall risk for stroke survivors.

How similar studies have performed: While the specific methods of perturbation training may be novel, similar studies have shown promise in improving balance and reducing falls in stroke patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Experience of a stroke at least 6 months prior to participation
* Self-reported experience of a fall in the previous year, and/or a fear of falling
* Gait speed of at least 0.2 m/s
* Ability to walk on a treadmill without a cane or walker
* Provision of informed consent

Exclusion Criteria:

* Evidence of cerebellar damage
* Resting blood pressure higher than 220/110 mm Hg
* History of unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during activities of daily living
* Preexisting neurological disorders or dementia
* Legal blindness or severe visual impairment
* History of DVT or pulmonary embolism within 6 months
* Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions
* Orthopedic injuries or conditions (e.g. joint replacements) in the lower extremities with the potential to alter the gait pattern

Where this trial is running

Charleston, South Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stroke

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.