Training to improve upper limb recovery after stroke
Interference During Motor Learning of Different Degrees of Freedom in the Paretic Upper Extremity of People With Stroke
This study is testing whether a special training program can help stroke survivors regain better movement in their arms by focusing on different joints separately.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 99 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | University of Valencia Academic / other |
| Locations | 2 sites (Valence, Valencia and 1 other locations) |
| Trial ID | NCT06249737 on ClinicalTrials.gov |
What this trial studies
This research focuses on enhancing post-stroke rehabilitation for the upper extremity by selectively training different degrees of freedom in movement. It aims to determine how training structure affects motor learning and performance in stroke survivors, particularly during the early subacute and chronic phases. The study will assess the impact of training one degree of freedom while minimizing interference from training another, using a structured four-day training program. The hypothesis suggests that training different joints may yield better outcomes than training the same joint.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with stroke who have sufficient muscular strength in their upper extremities.
Not a fit: Patients with other neurological or musculoskeletal conditions affecting upper limb mobility may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved rehabilitation strategies for upper limb recovery in stroke patients.
How similar studies have performed: While the specific approach of this study is novel, similar studies have shown promise in enhancing motor learning through targeted training techniques.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Stroke diagnosis * Muscular strength according to the MRC scale of 2 or more in the shoulder flexor, shoulder abductor and wrist extensor muscles. Exclusion Criteria: * Presence of another neurological or musculoskeletal disease that affects the mobility of the paretic upper extremity * Inability to follow instructions * Spasticity graded as 3 or more on the Modified Ashworth scale of flexor muscles of the upper extremity * Signs of cerebellar damage such as the presence of ataxia or dysmetria in the upper extremity
Where this trial is running
Valence, Valencia and 1 other locations
- Universitat de Valencia — Valence, Valencia, Spain (Recruiting)
- Unitat de dany Cerebral Adquirit — Valencia, Spain (Recruiting)
Study contacts
- Principal investigator: Trinidad Bruna-Melo, MSc — Universitat de Valencia
- Study coordinator: Trinidad Bruna-Melo, MSc
- Email: tribrume@uv.alumni.es
- Phone: +34657278264
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.