Training to improve balance after stroke
Official title: Optimal Intensity of Reactive Balance Training Post-stroke: a Randomized Controlled Trial
Run by Toronto Rehabilitation Institute · NCT06555016 · Data updated 2026-11-12
This study is testing whether higher intensity balance training can help stroke survivors improve their balance and reduce their risk of falling faster than lower intensity training.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 63 (estimated) |
| Sponsor | Toronto Rehabilitation Institute Academic / other |
| Locations | 1 site (Toronto, Ontario) |
| Status | Recruiting |
| Started | November 11, 2024 |
| Main results expected | June 2027 |
| Study ends | June 2028 |
| Registry record updated | October 1, 2026 |
| Trial ID | NCT06555016 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals who are more than six months post-stroke and can stand and walk independently.
✕Probably not a fit
Patients who have severe cognitive impairments, other neurological conditions affecting balance, or those currently receiving physiotherapy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of reactive balance training (RBT) in improving balance control and reducing fall risk in individuals who have experienced a stroke. The research aims to determine if higher intensity RBT can yield quicker improvements in balance reactions compared to lower intensity training. Participants will engage in exercises designed to challenge their balance through repeated perturbations, with the goal of enhancing their ability to react to loss of balance. The study will also explore how different training intensities affect the outcomes of balance training in stroke survivors.
Why it matters
Potential benefit: If successful, this study could significantly reduce the risk of falls in stroke survivors, improving their overall safety and quality of life.
How similar studies have gone: Previous studies have shown that reactive balance training can reduce fall rates in older adults and those with neurological conditions, suggesting potential success for this approach in stroke rehabilitation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Chronic stroke (\>6 months post-stroke) Exclusion Criteria: * Are unable to stand independently without upper-limb support for \>30 seconds and/or walk independently (without a gait aid) for ≥10 metres; * Have another neurological condition that could affect balance control (e.g., Parkinson's disease); * Have cognitive impairment (Montreal Cognitive Assessment8 score \<26), or severe language or communication difficulties affecting understanding instructions; * Have contraindications to RBT (has described by Mansfield et al., 2021), such as osteoporosis, activity restrictions due to cardiac event/surgery, or severe spasticity in the lower extremity; and/or * Are currently attending in- or out-patient physiotherapy or supervised exercise.
Where it's running
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Toronto Rehabilitation Institute
Toronto, Ontario, Canada Recruiting
Study contacts
- Principal investigator: Avril Mansfield, PhD — University Health Network, Toronto
- Study coordinator: Avril Mansfield, PhD
- Email: avril.mansfield@uhn.ca
- Phone: 416-597-3422
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
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Stem cell therapy for chronic stroke recovery
This study is testing whether using a patient's own stem cells can help people with long-term stroke recovery feel better and improve their daily functioning.
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AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
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Web-based therapy using action observation and mirror therapy for arm weakness after stroke
This trial tests whether a mobile telerehabilitation app delivering action observation therapy (AOT) alone or combined AOT with mirror therapy (AOT-MT) can improve upper limb function in people with subacute stroke.
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Remote Ischaemic Conditioning for Fatigue After Stroke 2
Aat least 12 weeks after stroke, adults with post-stroke fatigue will try a simple hand-arm cuff treatment at home to see if it helps reduce fatigue.
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Dual-task balance training plus computer-based cognitive training after stroke
In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.