Training to help manage subjective tinnitus using sound and self-phonation
Official title: Neuromodulatory Effects of Audio-proprio-phonatory Reinforcement Training on Subjective Tinnitus, Demonstrated by High-density Electroencephalogram (HD EEG)
Run by Centre Hospitalier Régional d'Orléans · NCT06880367 · Data updated 2026-11-12
This study tests if a new training method using sound and voice exercises can help people with chronic tinnitus feel better by masking their symptoms.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 84 Years |
| Sex | All |
| Enrollment | 56 (estimated) |
| Sponsor | Centre Hospitalier Régional d'Orléans Academic / other |
| Locations | 1 site (Orléans) |
| Status | Recruiting |
| Started | March 18, 2025 |
| Main results expected | September 18, 2028 |
| Study ends | September 18, 2028 |
| Registry record updated | December 30, 2025 |
| Trial ID | NCT06880367 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 85 who have been experiencing subjective tinnitus for more than three months.
✕Probably not a fit
Patients with objective tinnitus or those currently using white noise generators may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effects of audio-proprio-phonatory reinforcement training on individuals suffering from chronic subjective tinnitus. Participants will engage in self-phonation exercises to create sound stimuli that may help mask their tinnitus, while their brain activity is monitored using high-density electroencephalography (HD EEG). The study involves two groups that will alternate between training and no training phases, with assessments conducted at multiple visits to evaluate the impact of the intervention on tinnitus symptoms and brain connectivity. The goal is to quantify the therapeutic effects of this innovative approach.
Why it matters
Potential benefit: If successful, this approach could provide a novel, self-managed method for alleviating tinnitus symptoms.
How similar studies have gone: While the specific approach of audio-proprio-phonatory reinforcement is novel, similar neuromodulatory techniques have shown promise in managing tinnitus in other studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Person who agreed to participate in the study and gave consent * Aged ≥ 18 years and \< 85 years * Suffering from subjective tinnitus for more than 3 months * Have a score on the THI questionnaire taken at T0 greater than or equal to 38 * Be equipped with a smartphone compatible with the Siopi application and a computer connection for videoconference sessions * Have answered the questionnaires on the Siopi application: THI, VAS-D and associated questions and insomnia severity index * Have committed to diligently following the study protocol, including independent training * Have agreed not to take other new treatments for tinnitus throughout the duration of the study * Able to understand and carry out assessment instructions. Exclusion Criteria: * Patient suffering from objective tinnitus * Current port of white noise generators * Patient having consulted phoniatrics more than twice or having participated in more than two sound-mediated workshop sessions * Bilateral hearing loss \> 40 dB uncorrected on an audiogram or having declared serious or severe hearing loss on Siopi questionnaire, with or without prosthetic correction * New therapy introduced less than 2 months ago * Psychatric disorders causing auditory hallucinations * Protected person (under guardianship or curatorship) * Person under judicial protection * Person deprived of liberty * Person not affiliated to a social security system * Pregnant or breastfeeding woman * Person participating in a drug study
Where it's running
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CHU Orleans
Orléans, France Recruiting
Study contacts
- Principal investigator: Isabelle Dr MARIE-BAILLY, PhD — CHU Orléans
- Study coordinator: Isabelle Dr MARIE-BAILLY, PhD
- Email: isabelle.marie-bailly@chu-orleans.fr
- Phone: 2 38 74 43 28
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Non-Invasive Neurofeedback for Tinnitus Distress
This trial tests whether real-time neurofeedback training can reduce distress from tinnitus in adults with bothersome symptoms.
-
Neck nerve electrical stimulation combined with sound-frequency training for chronic tonal tinnitus
This trial tests whether pairing a safe electrical stimulation of the greater occipital nerve with an active sound-frequency training task can reduce tinnitus loudness and distress in adults with chronic tonal tinnitus.
-
Noninvasive ear cooling for tinnitus
This trial will try a noninvasive mild ear cooling device called ReBound to see if a single 30-minute session plus up to six months of home use reduces chronic subjective tinnitus in adults.
-
External mild-cooling therapy for chronic tinnitus
This test will see if wearing a mild external cooling device for 30 minutes can reduce symptoms in adults 18–55 with constant subjective tinnitus.
-
Walking with a dog to help tinnitus in sleep apnea patients
This study is testing if walking with a dog three times a week can help people with sleep apnea and tinnitus feel better compared to just following a diet.
-
Lifestyle changes for obese men with sexual dysfunction and tinnitus
This study is testing if a low-calorie diet combined with regular walking can help obese men with both sexual problems and ringing in their ears feel better.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.