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Clinical trial Recruiting at 1 site Interventional Ages 21 to 65

Training the diaphragm using ultrasound for patients on mechanical ventilation

Official title: Ultrasound Assessment of Diaphragmatic Muscle Exercise in Mechanically Ventilated Patients.

Run by Mansoura University · NCT04186325 · Data updated 2026-11-12

This study is testing if using ultrasound to help patients on mechanical ventilation strengthen their diaphragm can make it easier for them to breathe on their own again.

Quick facts

Study typeInterventional
Ages21 Years to 65 Years
SexAll
Enrollment70 (estimated)
SponsorMansoura University
Academic / other
Locations1 site (Al Mansurah)
StatusRecruiting
StartedDecember 28, 2019
Main results expectedOctober 31, 2028
Study endsDecember 31, 2029
Registry record updatedOctober 15, 2026
Trial IDNCT04186325 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients on mechanical ventilation due to neurological conditions who have consent from their legal guardians.

Probably not a fit

Patients with severe acute lung injury, morbid obesity, chest wall deformity, direct diaphragmatic injury, cervical spine issues, or those requiring neuromuscular infusion may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on patients who are on mechanical ventilation due to neurological conditions. It aims to evaluate the effectiveness of diaphragmatic exercising facilitated by ultrasound to improve the weaning process from mechanical ventilation. The approach involves careful monitoring and assessment of patients' clinical and neurological conditions to optimize the withdrawal from mechanical ventilation. The study seeks to reduce complications associated with prolonged mechanical ventilation, such as ventilator-associated pneumonia and extended hospital stays.

Why it matters

Potential benefit: If successful, this approach could enhance the weaning process from mechanical ventilation, leading to better clinical outcomes and reduced complications for patients.

How similar studies have gone: While the specific approach of diaphragmatic exercising with ultrasound is novel, similar interventions in mechanical ventilation weaning have shown promise in other studies.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* patients attached to mechanical ventilation will be included in the study after the informed consent of the legal guardian.

Exclusion Criteria:

* Patients with severe acute lung injury, morbid obesity, chest wall deformity, direct diaphragmatic injury, cervical spine and patients who require neuromuscular infusion will be excluded from the study.

Where it's running

  • Mansoura University-Emergency hospital-ICU
    Al Mansurah, Egypt     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.