Training the brain to enhance positive thinking using neurofeedback
Self-regulation of the MPFC Using Rt-fMRI NF Training to Enhance Positive Anticipation for Future Events
This study is testing if brain training with real-time feedback can help healthy people feel more positive and motivated about future events.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 35 Years |
| Sex | All |
| Sponsor | University of Electronic Science and Technology of China Academic / other |
| Locations | 1 site (Chengdu, Sichuan) |
| Trial ID | NCT06787248 on ClinicalTrials.gov |
What this trial studies
This trial investigates the effects of real-time fMRI neurofeedback on the medial prefrontal cortex (mPFC) to improve positive anticipation in healthy individuals. A total of 60 participants will be randomly assigned to either an experimental group receiving real neurofeedback or a control group receiving sham feedback. The study includes baseline and transfer sessions without feedback, along with multiple training sessions that provide real-time feedback on mPFC activity. The goal is to determine if participants can learn to control their mPFC activation and whether this control can enhance their motivation and anticipation for future events.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy individuals without any psychiatric or neurological disorders.
Not a fit: Patients with a history of brain injury or those with psychiatric or neurological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could help individuals enhance their positive thinking and motivation through targeted brain training.
How similar studies have performed: While neurofeedback has been explored in various contexts, this specific approach targeting the mPFC with positive episodic future thinking is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy subjects without any past or present psychiatric or neurological disorders Exclusion Criteria: * History of brain injury * Psychiatric or Neurological Disorder * Contraindications for MRI * Regular use of psychotropic substances (medication, drugs)
Where this trial is running
Chengdu, Sichuan
- University of Electronic Science and Technology of China(UESTC) — Chengdu, Sichuan, China (Recruiting)
Study contacts
- Study coordinator: Benjamin Becker, Dr
- Email: ben_becker@gmx.de
- Phone: 86-28-61830670
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.