Training for better diagnosis of lung diseases using cryobiopsy
Official title: Learning Curve for the Diagnosis of Interstitial Lung Disease by Transbronchial Lung Cryobiopsy and the Role of Standardized Training in It
Run by China-Japan Friendship Hospital · NCT06245954 · Data updated 2026-11-12
This study is testing whether special training for doctors on a lung biopsy technique can help them diagnose lung diseases more accurately.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | China-Japan Friendship Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | March 1, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | February 10, 2025 |
| Trial ID | NCT06245954 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older with suspected interstitial lung disease and specific pulmonary function criteria.
✕Probably not a fit
Patients with severe coagulopathy or those who refuse to participate in the study may not benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of standardized training methods, including simulator and in vitro lung training, for physicians performing transbronchial lung cryobiopsy (TBLC). It aims to assess the learning curve of these physicians and determine how structured training can improve diagnostic accuracy for interstitial lung disease (ILD). The study is designed as a prospective randomized controlled trial to ensure robust results. Participants will be monitored for their performance in TBLC after undergoing different training approaches.
Why it matters
Potential benefit: If successful, this study could enhance the diagnostic capabilities of physicians, leading to more accurate and timely diagnoses of interstitial lung disease.
How similar studies have gone: While the specific approach of standardized training in TBLC is novel, similar training methodologies in other medical procedures have shown promising results in improving physician performance.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years * suspected ILD. * ≤3 months since HRCT * Forced vital capacity (FVC) ≥50% of predicted value * Diffused lung carbon monoxide (DLCO) ≥35% predicted value * Echocardiography ≤ 12 months * Estimated pulmonary artery systolic pressure ≤40 mmHg * Body mass index (BMI) ≤35 kg/m2 * Patient consent for experimentation Exclusion Criteria: * Patients with platelet counts less than 50 × 109/L or prothrombin time international normalized ratio (INR) higher than 1.5 * Patients refused to participate in the experiment
Where it's running
-
China-Japan Friendship Hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Mingming Deng, MD
- Email: isdeng1017@163.com
- Phone: 86 18801336854
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.