Training breathing muscles to improve recovery after lung transplant
Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant: A Randomized Controlled Trial
This study is testing if training breathing muscles can help people recover better and feel healthier after having a lung transplant.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Jacksonville, Florida) |
| Trial ID | NCT04783155 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of inspiratory muscle training on exercise capacity, quality of life, and clinical outcomes in patients who have undergone lung transplantation. Participants will use the POWERBreathe Plus® device as part of their rehabilitation program. The goal is to determine if strengthening the muscles used for breathing can enhance recovery and overall health post-surgery.
Who should consider this trial
Good fit: Ideal candidates are individuals who have recently undergone single- or double-lung transplantation at Mayo Clinic Florida.
Not a fit: Patients who do not survive the transplant surgery or those undergoing retransplantation or multiorgan transplantation may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve recovery and quality of life for lung transplant patients.
How similar studies have performed: Previous studies have shown promising results with inspiratory muscle training in similar patient populations, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: \- All patients who undergo single- or double-lung transplant at Mayo Clinic Florida. Exclusion Criteria: * Patients who do not survive the intra-operative period during the transplant surgery. * Patients undergoing retransplantation. * Patients undergoing multiorgan transplantation. * Patients who are not willing to or who are unable to give written informed consent.
Where this trial is running
Jacksonville, Florida
- Mayo Clinic in Florida — Jacksonville, Florida, United States (Recruiting)
Study contacts
- Principal investigator: Bryan Taylor, PhD — Mayo Clinic
- Study coordinator: Bryan Taylor
- Email: taylor.bryan@mayo.edu
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.