Tracking COVID-19 antibody levels in hospital staff in Denmark

Seroconversion Among Staff at a Large Acute Care Hospital in Denmark During the COVID-19 Pandemic

Observational Nordsjaellands Hospital · NCT04431310

This study is testing how COVID-19 antibody levels change in hospital staff in Denmark to see who is protected and who might still be at risk during the pandemic.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorNordsjaellands Hospital Academic / other
Locations2 sites (Hillerød, Capital Region and 1 other locations)
Trial IDNCT04431310 on ClinicalTrials.gov

What this trial studies

This observational study aims to measure the seroconversion of SARS-CoV-2 antibodies among healthcare workers (HCWs) at two hospitals in Denmark during the COVID-19 pandemic. By collecting serum samples weekly and bi-weekly, the study will identify HCWs who are protected and non-infectious versus those who are seronegative and potentially at risk. The data gathered will help understand the transmission dynamics of COVID-19 among hospital staff and inform clinical practices. Additionally, long-term immunity will be assessed in a smaller group of seroconverted volunteers over a period of up to five years post-pandemic.

Who should consider this trial

Good fit: Ideal candidates for this study are hospital employees, including nurses, medical doctors, and laboratory scientists who have direct patient contact.

Not a fit: Patients who are not hospital employees or those who do not have direct contact with patients may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the safety protocols for healthcare workers and improve patient care during pandemics.

How similar studies have performed: Other studies have shown success in tracking seroconversion among healthcare workers during the pandemic, indicating that this approach is both relevant and tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria: hospital employee

-

Exclusion Criteria: none

Where this trial is running

Hillerød, Capital Region and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Covid-19Health PersonnelPersonnel, Hospitalhealthcare workershealth care workershcwseroconversion
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.