Clinical trial Recruiting at 1 site Observational

Tracking blood markers in aggressive Hodgkin and non-Hodgkin lymphoma

Official title: A Prospective Study for Patients With Lymphoma at the Samsung Medical Center

Run by Samsung Medical Center · NCT07032103 · Data updated 2026-11-12

This project will try to use blood tests (serum and cell-free DNA) to track treatment response and outcomes for adults with aggressive Hodgkin or non-Hodgkin lymphoma.

More Lymphoma trials

Quick facts

Study typeObservational
SexAll
Enrollment2000 (estimated)
SponsorSamsung Medical Center
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Seoul)
StatusRecruiting
StartedJune 1, 2022
Main results expectedDecember 30, 2028
Study endsDecember 30, 2028
Registry record updatedOctober 13, 2026
Trial IDNCT07032103 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20 or older with pathologically confirmed Hodgkin or non-Hodgkin aggressive lymphoma who require systemic chemotherapy with curative intent are ideal candidates.

Probably not a fit

Patients with myeloid malignancies, multiple myeloma, those who do not require systemic chemotherapy with curative intent, or patients under 20 are not expected to benefit from this project.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective cohort of adults with aggressive lymphomas who are receiving systemic chemotherapy at Samsung Medical Center. Patients may be newly diagnosed or have relapsed/refractory disease and will receive routine care per institutional practice. Researchers will collect serum and cell-free DNA from peripheral blood at baseline, interim, end of treatment, and at relapse, alongside standard laboratory and imaging assessments. Disease response and survival status will be updated regularly to correlate blood-based markers with clinical outcomes.

Why it matters

Potential benefit: If successful, the study could identify blood-based markers that help predict treatment response and relapse, enabling earlier intervention and more personalized follow-up.

How similar studies have gone: Previous work has shown circulating tumor DNA and other blood markers can track disease and predict relapse in lymphoma, but their routine clinical use is still emerging.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Pathologically diagnosed Hodgkin and non-Hodgkin lymphomas
2. 20 years
3. Patients requiring systemic chemotherapy with curative intent
4. Written informed consent

Exclusion Criteria:

1. Myeloid malignancy
2. Multiple myeloma
3. Patients do not require systemic chemotherapy with curative intent

Where it's running

  • Samsung Medical Center
    Seoul, South Korea
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.