Tracking blood markers in aggressive Hodgkin and non-Hodgkin lymphoma
Official title: A Prospective Study for Patients With Lymphoma at the Samsung Medical Center
Run by Samsung Medical Center · NCT07032103 · Data updated 2026-11-12
This project will try to use blood tests (serum and cell-free DNA) to track treatment response and outcomes for adults with aggressive Hodgkin or non-Hodgkin lymphoma.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 2000 (estimated) |
| Sponsor | Samsung Medical Center Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Seoul) |
| Status | Recruiting |
| Started | June 1, 2022 |
| Main results expected | December 30, 2028 |
| Study ends | December 30, 2028 |
| Registry record updated | October 13, 2026 |
| Trial ID | NCT07032103 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 20 or older with pathologically confirmed Hodgkin or non-Hodgkin aggressive lymphoma who require systemic chemotherapy with curative intent are ideal candidates.
✕Probably not a fit
Patients with myeloid malignancies, multiple myeloma, those who do not require systemic chemotherapy with curative intent, or patients under 20 are not expected to benefit from this project.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective cohort of adults with aggressive lymphomas who are receiving systemic chemotherapy at Samsung Medical Center. Patients may be newly diagnosed or have relapsed/refractory disease and will receive routine care per institutional practice. Researchers will collect serum and cell-free DNA from peripheral blood at baseline, interim, end of treatment, and at relapse, alongside standard laboratory and imaging assessments. Disease response and survival status will be updated regularly to correlate blood-based markers with clinical outcomes.
Why it matters
Potential benefit: If successful, the study could identify blood-based markers that help predict treatment response and relapse, enabling earlier intervention and more personalized follow-up.
How similar studies have gone: Previous work has shown circulating tumor DNA and other blood markers can track disease and predict relapse in lymphoma, but their routine clinical use is still emerging.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Pathologically diagnosed Hodgkin and non-Hodgkin lymphomas 2. 20 years 3. Patients requiring systemic chemotherapy with curative intent 4. Written informed consent Exclusion Criteria: 1. Myeloid malignancy 2. Multiple myeloma 3. Patients do not require systemic chemotherapy with curative intent
Where it's running
-
Samsung Medical Center
Seoul, South Korea Recruiting
Study contacts
- Study coordinator: Seok Jin Kim, MD., PhD.
- Email: kstwoh@gmail.com
- Phone: +82234101766
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.