Topical Vitamin D for Treating Female Pattern Hair Loss

Efficacy and Safety of Topical Vitamin D Analogue in Treatment of Female Pattern Hair Loss

Phase1; Phase2 Interventional Sohag University · NCT06333600

This study is testing if a special vitamin D cream can help women with hair loss feel better and improve their hair growth.

Quick facts

PhasePhase1; Phase2
Study typeInterventional
Enrollment45 (estimated)
Ages15 Years to 60 Years
SexFemale
SponsorSohag University Academic / other
Locations1 site (Sohag)
Trial IDNCT06333600 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the efficacy and safety of a topical vitamin D analogue in treating female pattern hair loss (FPHL). It is a prospective, randomized, controlled study involving 45 females aged 15-70 who have been diagnosed with FPHL and have low serum vitamin D levels. Participants will be monitored for their response to the treatment, which includes topical minoxidil and saline spray, while ensuring strict exclusion criteria to maintain study integrity.

Who should consider this trial

Good fit: Ideal candidates are females aged 15-60 years diagnosed with female pattern hair loss and low serum vitamin D levels.

Not a fit: Patients with other types of hair loss disorders or those with normal serum vitamin D levels will not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a new therapeutic option for women suffering from hair loss due to vitamin D deficiency.

How similar studies have performed: While there is limited data on the use of topical vitamin D analogues for hair loss, similar approaches in dermatology have shown promise, making this study a potentially novel exploration.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All females with FPHL aging 15 - 60 years

Exclusion Criteria:

* Patients with other hair loss disorders as telogen effluvium, anagen effluvium, alopecia areata, cicatricial alopecia and trichotillomania.

  * Patients with normal serum vit.D level
  * Oral or parentral vitamin D supplementation for the last 3 months
  * Treatment with topical vitamin D analogs in the past month
  * Patients who received hair tonics or any specific hair therapy over the last 3 months prior to enrollement in the study.
  * Patients with diabetes mellitus, renal disease, thyroid and parathyroid abnormalities, or autoimmune diseases.
  * Patients who are pregnant, lactating or on contraceptive pills.

Where this trial is running

Sohag

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions DermatologyFemale Pattern Baldness
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.