Topical cream for treating post-inflammatory hyperpigmentation in Malaysians
Safety and Efficacy of Topical Cream Containing Natural Plant Extracts, Niacinamide, and Arbutin for Post-inflammatory Hyperpigmentation Skin Among Malaysians
This study is testing a new cream made with niacinamide and plant extracts to see if it can help Malaysian adults reduce dark spots on their skin caused by inflammation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 25 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre Industry-sponsored |
| Locations | 1 site (Petaling Jaya, Selangor) |
| Trial ID | NCT05986123 on ClinicalTrials.gov |
What this trial studies
This study evaluates the safety and efficacy of a topical cream containing niacinamide, arbutin, and various plant extracts for treating post-inflammatory hyperpigmentation (PIH) in Malaysian adults. Over a 20-week period, participants will apply the cream and undergo skin assessments at multiple intervals to measure its effectiveness and safety. The study aims to determine how well the cream works and how satisfied users are with the treatment.
Who should consider this trial
Good fit: Ideal candidates are healthy Malaysian adults aged 18 to 40 with post-inflammatory hyperpigmentation.
Not a fit: Patients with existing skin disorders or those who have recently undergone cosmetic treatments may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide an effective solution for individuals suffering from post-inflammatory hyperpigmentation.
How similar studies have performed: While there have been studies on topical treatments for hyperpigmentation, this specific combination of ingredients in the Malaysian population is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Malaysia citizen * Healthy adult, aged between 18 to 40 years old. * Participants who have post-inflammatory hyperpigmentation on skin Exclusion Criteria: * Participants with skin disorders such as skin infection or skin inflammation. * Participants who have undergone any skin and cosmetic treatments such as dermal fillers, botox, laser, chemical peels within the last 3 months. * Participant who is taking isotretinoin for the past 6 or 12 months and immunocompromised patients. * Pregnant, breastfeeding women or planned for pregnancy during the study period.
Where this trial is running
Petaling Jaya, Selangor
- Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre — Petaling Jaya, Selangor, Malaysia (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.