Tool for shared decision making on drug interactions in anticoagulant therapy

Implementation of DDInteract A Shared-decision Making Tool for Anticoagulant Drug-Drug INTERACTions (DDinteract)

Not applicable Interventional University of Utah · NCT06401863

This study is testing a new tool to help doctors and patients make better decisions about managing drug interactions for people taking blood thinners.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment3691 (estimated)
Ages21 Years and up
SexAll
SponsorUniversity of Utah Academic / other
Locations3 sites (Denver, Colorado and 2 other locations)
Trial IDNCT06401863 on ClinicalTrials.gov

What this trial studies

This project aims to implement and evaluate a shared decision-making tool called DDInteract, designed to assist healthcare providers and patients in managing drug interactions while on oral anticoagulants. The tool will be integrated into electronic health records (EHR) at three university-based healthcare systems, allowing for the retrieval of patient-specific risk factors and the calculation of potential harm from drug interactions. By enabling dynamic exploration of treatment scenarios, DDInteract seeks to optimize patient care and minimize risks associated with anticoagulant therapy. The study will also assess the effectiveness of DDInteract in real-world settings and identify barriers to its adoption.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 21 and older who are prescribed multiple oral anticoagulants.

Not a fit: Patients who are unable to speak English or Spanish will not benefit from this study due to language barriers.

Why it matters

Potential benefit: If successful, this tool could significantly enhance patient safety by reducing the risk of harmful drug interactions in patients on anticoagulants.

How similar studies have performed: Other studies have shown promise in using shared decision-making tools for medication management, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Be at least 21 years of age or older
* Receive more than one prescription of an oral anticoagulant (i.e. warfarin, apixaban, edoxaban, dabigatran, rivaroxaban)

Exclusion Criteria:

* Individuals not able to speak English or Spanish

Where this trial is running

Denver, Colorado and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AnticoagulantsDrug InteractionsOral anticoagulantsDrug interactionsGastrointestinal hemorrhageShared Decision Making
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.