Timing of oxytocin use during labor and its effects on delivery outcomes
Association Between Time of Oxytocin Initiation at 2nd Stage of Labor and Adverse Outcomes
This study is testing if giving oxytocin earlier during the second stage of labor can help women have vaginal deliveries and reduce the time spent in that stage.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Rambam Health Care Campus Academic / other |
| Locations | 1 site (Haifa) |
| Trial ID | NCT06181396 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of early oxytocin administration during the second stage of labor on delivery outcomes, particularly focusing on rates of vaginal delivery and the duration of the second stage. It aims to address the rising rates of cesarean deliveries and associated maternal and neonatal complications by evaluating the timing of oxytocin initiation. The study will include women with singleton pregnancies who receive oxytocin during labor, comparing outcomes to those who do not. The goal is to establish a more effective protocol for oxytocin use that could lead to improved delivery experiences.
Who should consider this trial
Good fit: Ideal candidates for this study are women aged 18 and older with singleton pregnancies who are receiving oxytocin during the second stage of labor.
Not a fit: Patients with multiple gestations, known fetal malformations, or uterine scars may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to reduced cesarean delivery rates and improved maternal and neonatal health outcomes.
How similar studies have performed: Other studies have shown that early oxytocin administration can improve delivery outcomes, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Singleton pregnancy 2. Maternal age ≥ 18 years' old 3. Oxytocin administration initiated or renewed during second stage of labor Exclusion Criteria: 1. Maternal age \< 18 years' old 2. Multiple gestation pregnancy 3. Known fetal malformations 4. Uterine scar
Where this trial is running
Haifa
- Rambam medical health campus — Haifa, Israel (Recruiting)
Study contacts
- Study coordinator: Gal Bachar, MD
- Email: g_bachar@rambam.health.gov.il
- Phone: +97247771449
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.