TIMELY-PrädiktoR: predicting who benefits from cardiac rehabilitation
TIMELY-PrädiktoR Prospective Study
The project will collect detailed health, lifestyle, and rehab data from people with coronary artery disease in phase II cardiac rehabilitation to see if AI can find patterns that predict who benefits most.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Witten/Herdecke Academic / other |
| Locations | 1 site (Ennepetal, North Rhine-Westphalia) |
| Trial ID | NCT05461729 on ClinicalTrials.gov |
What this trial studies
TIMELY-PrädiktoR is an observational program that gathers high-resolution clinical, behavioral, and remote-monitoring data from coronary artery disease patients participating in phase II cardiac rehabilitation. The protocol records biological, psychological, and social variables alongside telemedicine and lifestyle measures to build a comprehensive dataset. Machine-learning and data-mining methods will be applied to identify intra-individual factors and interactions linked to rehabilitation success and future risk. Participants receive standard cardiac rehabilitation while data are collected at Klinik Königsfeld for analysis.
Who should consider this trial
Good fit: Adults with coronary artery disease after myocardial infarction, angioplasty/PCI, or coronary artery bypass who are enrolled in and able to participate in phase II cardiac rehabilitation and can provide informed consent.
Not a fit: Patients with unstable coronary or cerebrovascular conditions, acute infections, or those unable to participate in phase II cardiac rehabilitation or to give informed consent are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, this work could enable more personalized cardiac rehabilitation by predicting which patients will respond best to specific interventions, improving recovery and reducing future cardiac events.
How similar studies have performed: Previous research using remote monitoring and artificial intelligence to predict cardiac outcomes has shown promising but still exploratory results rather than definitive clinical adoption.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Coronary Artery Disease (CAD) patients after myocardial infarction (STEMI/NSTEMI) and/or angioplasty and/or Percutaneous Coronary Intervention (PCI) and/or coronary artery bypass graft surgery who participate in phase II Cardiac Rehabilitation (CR). Exclusion Criteria: * Incapability to give informed consent * Conditions that prevent patients from participation in CR including unstable coronary or cerebrovascular conditions and acute infections
Where this trial is running
Ennepetal, North Rhine-Westphalia
- Klinik Königsfeld — Ennepetal, North Rhine-Westphalia, Germany (Recruiting)
Study contacts
- Principal investigator: Boris Schmitz, PhD — University of Witten/Herdecke, Dpt. Rehabilitation Sciences
- Study coordinator: Boris Schmitz, PhD
- Email: boris.schmitz@uni-wh.de
- Phone: 004923339888156
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.