Thyroid problems and acute coronary syndrome in hospitalized patients
Study Of Thyroid Disorders In Patients With Acute Coronary Syndrome At Sohag University Hospitals .
This project will test whether thyroid problems are common and linked to acute coronary syndrome in people admitted to the coronary care unit.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT07082712 on ClinicalTrials.gov |
What this trial studies
This observational study will enroll 300 patients aged over 20 who are hospitalized with acute coronary syndrome at Sohag University hospitals. Each participant will have a detailed medical history, clinical exam, and laboratory testing including TSH, free T3, free T4 collected within 24 hours of CCU admission, plus serum lipids and cardiac enzymes. Patients already treated for thyroid disease, with acute decompensated heart failure, advanced malignancy, or acute pulmonary thromboembolism will be excluded. The study aims to determine the prevalence of thyroid dysfunction in ACS patients and its relationship with established coronary risk factors.
Who should consider this trial
Good fit: Adults older than 20 who are hospitalized with a diagnosis of acute coronary syndrome and are not already receiving treatment for thyroid disease.
Not a fit: Patients already on treatment for hypothyroidism or hyperthyroidism, or those with acute decompensated heart failure, advanced cancer, or acute pulmonary embolism are excluded and unlikely to benefit from participation.
Why it matters
Potential benefit: If results show a clear link, clinicians could more readily detect and consider thyroid dysfunction when managing patients with acute coronary syndrome.
How similar studies have performed: Prior observational studies have reported associations between abnormal thyroid tests and worse cardiac outcomes, though results have varied between populations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients more than 20 years old who were diagnosed with ACS. Exclusion Criteria: - Patients known hypothyroidism or hyperthyroidism on treatment. Patients presented by acute decompensated heart failure. Patients with advanced malignancies. Patients with acute pulmonary thromboembolism.
Where this trial is running
Sohag
- Faculty of medicine sohag University — Sohag, Egypt (Recruiting)
Study contacts
- Principal investigator: Asmaa AbuBakr "MohamedAl-Mobdy " — Tertiary hospital
- Study coordinator: Asmaa AbuBakr "MohamedAl-Mobdy "
- Email: asmaa_abubakr_post@med.Sohag.edu.eg
- Phone: 01100799603
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.