Thyroid problems and acute coronary syndrome in hospitalized patients
Official title: Study Of Thyroid Disorders In Patients With Acute Coronary Syndrome At Sohag University Hospitals .
Run by Sohag University · NCT07082712 · Data updated 2026-11-12
This project will test whether thyroid problems are common and linked to acute coronary syndrome in people admitted to the coronary care unit.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Status | Recruiting |
| Started | June 28, 2025 |
| Main results expected | September 1, 2025 |
| Study ends | November 1, 2025 |
| Registry record updated | July 24, 2025 |
| Trial ID | NCT07082712 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults older than 20 who are hospitalized with a diagnosis of acute coronary syndrome and are not already receiving treatment for thyroid disease.
✕Probably not a fit
Patients already on treatment for hypothyroidism or hyperthyroidism, or those with acute decompensated heart failure, advanced cancer, or acute pulmonary embolism are excluded and unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study will enroll 300 patients aged over 20 who are hospitalized with acute coronary syndrome at Sohag University hospitals. Each participant will have a detailed medical history, clinical exam, and laboratory testing including TSH, free T3, free T4 collected within 24 hours of CCU admission, plus serum lipids and cardiac enzymes. Patients already treated for thyroid disease, with acute decompensated heart failure, advanced malignancy, or acute pulmonary thromboembolism will be excluded. The study aims to determine the prevalence of thyroid dysfunction in ACS patients and its relationship with established coronary risk factors.
Why it matters
Potential benefit: If results show a clear link, clinicians could more readily detect and consider thyroid dysfunction when managing patients with acute coronary syndrome.
How similar studies have gone: Prior observational studies have reported associations between abnormal thyroid tests and worse cardiac outcomes, though results have varied between populations.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients more than 20 years old who were diagnosed with ACS. Exclusion Criteria: - Patients known hypothyroidism or hyperthyroidism on treatment. Patients presented by acute decompensated heart failure. Patients with advanced malignancies. Patients with acute pulmonary thromboembolism.
Where it's running
-
Faculty of medicine sohag University
Sohag, Egypt Recruiting
Study contacts
- Principal investigator: Asmaa AbuBakr "MohamedAl-Mobdy " — Tertiary hospital
- Study coordinator: Asmaa AbuBakr "MohamedAl-Mobdy "
- Email: asmaa_abubakr_post@med.Sohag.edu.eg
- Phone: 01100799603
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.