Thulium laser with growth-factor serum (with or without LED) for androgenetic hair loss
Thulium Laser and Growth Factors for Androgenetic Alopecia - a Prospective, Clinical Study
This trial tests whether thulium laser plus a growth-factor serum, with or without added LED light, can improve hair growth in adults with androgenetic alopecia.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universitätsklinikum Hamburg-Eppendorf Academic / other |
| Locations | 1 site (Hamburg, Free and Hanseatic City of Hamburg) |
| Trial ID | NCT07079657 on ClinicalTrials.gov |
What this trial studies
This interventional trial compares three treatment approaches for adults with androgenetic alopecia: thulium laser alone, thulium laser with a topical growth-factor serum, and thulium laser with growth-factor serum combined with LED phototherapy. Participants are adults aged 18 and over without scarring alopecia or major contraindications and will receive treatments and scheduled follow-up visits at a single center. Outcomes include objective hair measurements and patient-reported hair and scalp satisfaction to capture both clinical and patient-side effects. The protocol excludes pregnant or breastfeeding women, recent resurfacing procedures, metallic head implants, significant scalp wounds, and other specified contraindications.
Who should consider this trial
Good fit: Adults aged 18 and older with non-scarring androgenetic alopecia who are in good general health and able to attend clinic visits are ideal candidates.
Not a fit: People with scarring or non-androgenetic hair loss, recent scalp resurfacing, significant open scalp wounds, metallic cranial implants, or who are pregnant or breastfeeding are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, this approach could provide a minimally invasive option to increase hair density and improve patient satisfaction for people with pattern hair loss.
How similar studies have performed: Some small studies and clinical experience suggest laser and growth-factor combinations may help hair regrowth, but robust, controlled evidence is currently limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and women aged 18 and over * Good general health, no relevant previous illnesses * Presence of an AGA * Cognitive ability and willingness to give consent (informed consent) * Be willing and able to attend follow-up visits Exclusion Criteria: * Age \< 18 years * Pregnant or breastfeeding women * Scarring alopecia, alopecia due to dermatoses (e.g. lichen ruber, lupus erythemodes,...), alopecia due to chemical or physical noxae, and other non-AGAs * Significant scarring of the region to be treated * Significant open wounds or lesions in the region to be treated * Metallic implants in the head region * Mental illnesses (psychoses, body perception disorders) * Use of isotretinoin or other retinoids, psychotropic drugs, coumarins or heparins in the last 2 weeks * Resurfacing (fractional, ablative, non-ablative) of the affected region \< 2 months before and during the study period * Tendency to excessive scarring * Lack of informed consent and/or data protection declarations
Where this trial is running
Hamburg, Free and Hanseatic City of Hamburg
- University Medical Center Hamburg-Eppendorf — Hamburg, Free and Hanseatic City of Hamburg, Germany (Recruiting)
Study contacts
- Study coordinator: Lynhda Nguyen, Dr. med.
- Email: l.nguyen@uke.de
- Phone: +49 (0)40 7410 54289
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.