Thrombus aspiration for heart attack patients with high thrombus burden

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of thrombus aspiration in patients experiencing ST-segment Elevation Myocardial Infarction (STEMI) with a high thrombus burden during primary percutaneous coronary intervention (PCI). It is a multicenter, open-label, randomized controlled trial where participants are assigned to receive either thrombus aspiration or standard PCI treatment. The goal is to determine if thrombus aspiration can reduce the risk of serious cardiovascular events within 180 days and stroke within 30 days after treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥ 18 years;
2. STEMI patients undergoing primary PCI within 12 hours after the onset of symptoms;
3. High thrombus burden after guidewire passes the lesion (TIMI thrombus grade ≥3);
4. Informed consent must be voluntary;

Exclusion Criteria:

1. Haemodynamic instability or cardiogenic shock;
2. After thrombolytic therapy;
3. The predicted survival time is less than 6 months due to non-cardiac disease;
4. History of coronary artery bypass grafting;
5. Participate in other researches within 30 days;
6. Preoperative gastrointestinal bleeding or contraindications to dual antiplatelet therapy;
7. Patients were considered unsuitable by other researchers.

Where it's running

• First People's Hospital of Foshan
  Foshan, Guangdong, China Recruiting
• The Second People's Hospital of Nanhai District
  Foshan, Guangdong, China Recruiting
• First People's Hospital of Shunde (Affiliated Hospital at Shunde, Southern Medical University)
  Foshan, Guangdong, China Recruiting
• Guangdong Provincial People's Hospital
  Guangzhou, Guangdong, China Recruiting
• Jiangmen Central Hospital
  Jiangmen, Guangdong, China Recruiting
• Kaiping Central Hospital
  Kaiping, Guangdong, China Recruiting

Study contacts

• Study coordinator: Pengcheng He, MD
• Email: drhepengcheng@aliyun.com
• Phone: 86-13829730152

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Administering adrenaline in STEMI patients during PCI to prevent no reflow

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.