THRIVE-CAR-T mobile app to support people receiving CAR T therapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot randomized controlled trial compares the THRIVE-CAR-T supportive care mobile app to usual care for adults undergoing autologous CAR-T therapy at Massachusetts General Hospital. Participants are randomized to use the app or receive standard supportive care, with patient-reported outcomes collected during the peri-infusion period. The primary aims are to determine feasibility and acceptability, while exploratory analyses will look at preliminary effects on quality of life, psychological distress, and self-efficacy. Outcomes include validated patient-reported measures and feasibility metrics such as enrollment, retention, and app usage.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 18 years or older
2. Ability to understand English
3. Diagnosis of a hematologic malignancy
4. Receiving autologous CAR-T at MGH with an FDA approved cellular therapy product

Exclusion Criteria:

1. Impaired cognition or uncontrolled mental illness that prohibits the ability to provide informed consent based on the oncology clinician assessment
2. Already participating in another supportive care clinical trial

Where it's running

• Massachusetts General Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Study coordinator: Patrick C Johnson, MD
• Email: pcjohnson@mgh.harvard.edu
• Phone: 6177244000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.