Clinical trial Recruiting at 1 site Interventional Ages 20 to 40

Thoracic thrust plus gentle neck mobilization for chronic mechanical neck pain

Official title: Thoracic Thrust With Cervical Non-Thrust Mobilization in Mechanical Neck Pain

Run by Foundation University Islamabad · NCT07326696 · Data updated 2026-11-12

This trial will test whether adding a quick thoracic thrust to gentle neck mobilization helps adults aged 20–40 with chronic mechanical neck pain have less pain and better movement.

Quick facts

Study typeInterventional
Ages20 Years to 40 Years
SexAll
Enrollment46 (estimated)
SponsorFoundation University Islamabad
Academic / other
Locations1 site (Islamabad, Punjab Province)
StatusRecruiting
StartedJanuary 25, 2025
Main results expectedDecember 30, 2025
Study endsJanuary 15, 2026
Registry record updatedJanuary 8, 2026
Trial IDNCT07326696 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20–40 with chronic (>3 months) mechanical neck pain, cervical (C2–C7) and thoracic (T1–T6) hypomobility, and a craniovertebral angle under 48 degrees are the intended candidates.

Probably not a fit

Patients with serious pathology (e.g., neoplasm, fracture), recent whiplash, cervical spinal stenosis, radiculopathy or neurological deficits, structural deformities, vertebrobasilar insufficiency, pregnancy, or prior cervical/thoracic spine surgery are excluded and unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial in Islamabad will use a coin-toss to assign adults with chronic mechanical neck pain to one of two groups. One group will receive a thoracic thrust manipulation alongside cervical non-thrust mobilization and therapeutic exercises, while the other group will receive cervical non-thrust mobilization with exercises alone. Researchers will measure pain, thoracic range of motion, kyphotic angle, craniovertebral angle, and neck proprioception before and after the intervention. Comparisons will focus on short-term changes between the two treatment approaches.

Why it matters

Potential benefit: If successful, adding thoracic thrusts could provide faster pain relief and improved neck and upper-back mobility compared with neck mobilization alone.

How similar studies have gone: Prior randomized trials of thoracic manipulation added to cervical care have shown short-term reductions in neck pain and improved range of motion, though long-term superiority is inconsistent.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

* Both male and female
* Age: 20-40 years
* Numeric pain rating scale (3\<) (13)
* Neck pain for more than 3 months
* Cervical hypomobility (C2-C7)
* Thoracic hypomobility (T1-T6)
* CranioVertebral Angle \< 48 Degrees

Exclusion criteria:

* Serious pathology (e.g. neoplasm, fracture)
* History of whiplash injury within the past 6 months
* Cervical spinal stenosis
* Radiculopathy
* Neurological deficit
* Structural deformities
* Vertebrobasilar artery insufficiency
* Pregnancy
* Prior surgery of cervical or thoracic spine

Where it's running

  • Foundation University College of Physical Therapy
    Islamabad, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.