Therapy to improve control and reduce symptoms in children with non-epileptic seizures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of Retraining and Control Therapy (ReACT) in treating pediatric patients aged 9-18 diagnosed with psychogenic non-epileptic seizures (PNES). Participants will undergo twelve therapy sessions aimed at enhancing their sense of control and reducing catastrophic symptom expectations. The study employs various assessments, including pain tolerance tests and cortisol measurements, to gauge the therapy's impact. Follow-up visits will occur at 6 and 12 months post-treatment to monitor long-term outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 9-18 years old.
* Diagnosis of psychogenic non-epileptic seizures by a medical doctor using video-EEG.
* Family member (parent if a minor) willing to participate and that the subject with PNES chooses.

Exclusion Criteria:

* Comorbid Epilepsy
* Less than 4 PNES per month
* Other paroxysmal nonepileptic events (e.g. episodes related to hypoxic-ischemic phenomena, sleep disorders or migraine-associated disorders)
* Participation in other therapy
* Severe intellectual disability
* Severe mental illness (delusions/hallucinations)

Exclusion for CPT:

* Blood pressure \>130/80 mmHg for adolescents greater than or equal to 13 years old
* Either systolic and/or diastolic blood pressure greater than or equal to 95% based on sex and age for children less than 13 years old

Where it's running

• Sparks Center Office of Psychiatric Research
  Birmingham, Alabama, United States Recruiting

Study contacts

• Study coordinator: Aaron Fobian, PhD
• Email: afobian@uabmc.edu
• Phone: 205-934-2241

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Retraining and Control Therapy for adults with non-epileptic seizures

  This study is testing a new therapy called Retraining and Control Therapy to see if it can help adults with non-epileptic seizures feel more in control and reduce their worries about their symptoms.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06570954

• Creating a treatment program for functional neurological disorder

  This study is trying to create a new treatment plan for people with functional neurological disorder by bringing together different types of therapy to see if it helps both kids and adults feel better.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06362161

• Therapy to improve control and reduce symptoms in children with non-epileptic seizures

  This study is testing a new therapy called ReACT to see if it can help children aged 11-18 with non-epileptic seizures feel more in control and reduce their symptoms.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT06007053

• Feasibility of a new mind and body treatment for pediatric functional seizures

  This study is testing if two different treatments for kids with functional seizures work well enough to be used in a larger trial.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT05819268

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.