Therapist-guided online CBT for adults with chronic physical health conditions
Official title: Therapist-Guided Internet-Delivered Cognitive Behaviour Therapy (CBT) for Chronic Conditions (Chronic Conditions Course; CCC): Single-Group Predictors of Change in Routine Care
Run by University of Regina · NCT07233980 · Data updated 2026-11-12
This project tests whether a therapist-guided online cognitive behavioral therapy course helps adults in Saskatchewan with chronic physical health conditions who have anxiety or depression.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 260 (estimated) |
| Sponsor | University of Regina Academic / other |
| Locations | 2 sites (Regina, Saskatchewan and 1 other locations) |
| Status | Recruiting |
| Started | October 8, 2025 |
| Main results expected | October 2026 |
| Study ends | December 2026 |
| Registry record updated | December 2, 2025 |
| Trial ID | NCT07233980 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older who live in Saskatchewan, have a self-reported diagnosed chronic physical health condition affecting their mental health, have internet access, and consent to treatment/research are eligible.
✕Probably not a fit
People with current severe psychiatric or medical conditions that need immediate treatment (e.g., active psychosis, mania, imminent suicide risk, urgent surgery), significant cognitive difficulties, or those living outside Saskatchewan are unlikely to benefit from or be eligible for this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The program delivers a transdiagnostic internet-delivered cognitive behavioral therapy course (the Chronic Conditions Course, CCC) with therapist guidance through the Online Therapy Unit. Adults with diverse chronic physical health conditions complete the online modules while registered therapists provide personalized support to enhance adherence and treatment relevance. The study also analyzes which factors predict improvement, focusing on baseline symptom severity, adherence, treatment credibility, and therapeutic alliance. Outcomes include changes in depression, anxiety, disability, and other patient-reported measures collected during routine care and follow-up.
Why it matters
Potential benefit: If successful, the CCC could reduce anxiety, depression, and disability for people with chronic conditions while using substantially less clinician time and improving access to care.
How similar studies have gone: Previous large randomized trials of the CCC by Dear and colleagues have shown significant and durable reductions in depression, anxiety, and disability, with effects comparable to face-to-face care.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Saskatchewan resident (as funding is provided by Saskatchewan government); * Aged 18 years or older; * self-reported diagnosed with chronic physical health condition affecting mental health; * Access to a computer and the Internet; * Consent to treatment/research Exclusion Criteria: * Current severe psychiatric or medical condition that requires immediate treatment and or would interfere with participation (e.g. current mania or psychosis, actively suicidal or unable to keep themselves safe, medical condition requiring immediate surgery or other invasive treatment, cognitive difficulties); * Taking part in another treatment in our clinic; * Living outside of Saskatchewan
Where it's running
-
Online Therapy Unit
Regina, Saskatchewan, Canada Recruiting -
Online Therapy Unit, University of Regina
Regina, Saskatchewan, Canada Not yet recruiting
Study contacts
- Principal investigator: Heather Hadjistavropoulos, PhD — University of Regina
- Study coordinator: Marcie Nugent, MSW
- Email: marcie.nugent@uregina.ca
- Phone: 306-337-3331
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.