Testosterone levels and coronary lesion complexity in young men

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study enrolls men under 45 with premature ischemic heart disease who are scheduled for elective coronary angiography. Investigators will measure serum testosterone and determine lesion complexity using the SYNTAX score from the angiograms. The analysis will look for associations between testosterone level and angiographic complexity while adjusting for traditional cardiovascular risk factors. Results aim to clarify whether hormonal status relates to the severity and complexity of early-onset coronary artery disease.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male patients aged \<45 years.
* Diagnosed with premature ischemic heart disease.
* Undergoing elective coronary angiography for suspected coronary artery disease (CAD) .

Exclusion Criteria:

* History of acute coronary syndrome within the preceding 3 months.
* Prior diagnosis of hypogonadism or history of testosterone replacement therapy or anabolic steroid use.
* Active neoplasm or history of chemotherapy.
* Known hepatic cirrhosis, chronic kidney disease, or end-stage renal disease.
* Use of medications known to affect sex hormone levels (e.g., spironolactone, ketoconazole).
* Endocrine disorders such as sickle cell anemia or celiac disease.

Where it's running

• Sohag University
  Sohag, Egypt Recruiting

Study contacts

• Study coordinator: Remon S Adly, MD
• Email: remonsaleh@yahoo.com
• Phone: 00201221878986

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.