Testing two doses of a muscle relaxant for drowsiness in healthy adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthy adults will take one dose after a meal, undergo drowsiness and fall-risk testing at peak blood levels, and have EEG monitoring during testing. After a one-week washout, they will receive the second dose with the same testing sequence for comparison. The trial is a randomized, crossover-like comparison of two dosages, conducted at a single site.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy adults aged 18 to 55 years old
* Weigh at least 120 pounds
* Medically healthy
* Able to sign and date informed consent form

Exclusion Criteria:

* Current use of any medications known to affect the sleep-wake cycle
* Sleep disorder diagnosis
* Positive urine test for drugs
* Known history of alcohol use disorder
* Having a history of cognitive disorders, depression, schizophrenia, panic disorder, or dementia
* Having difficulty eating high fat meal
* Participants who are pregnant, nursing or intending to become pregnant during the period of study.
* Blood Pressure \> 160/110 or \<90/50 mmHg.
* Heart Rate \>100 or \< 50/ beats per minute.
* Having a history of seizure disorder or epilepsy.

Where it's running

• AMR Clinical - Columbus
  Columbus, Ohio, United States Recruiting

Study contacts

• Study coordinator: Project Manager
• Email: mshahbandar@primusrx.com
• Phone: 480-483-1410

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.