Testing the Glasgow-Blatchford bleeding score in Tunisian adults with upper gastrointestinal bleeding
External Validation of the Glasgow-Blatchford Bleeding Score in a Tunisian Population
Hôpital Universitaire Sahloul · NCT07089277
This project will see if the Glasgow‑Blatchford Score can predict 30‑day complications in adults in Tunisia who come to the emergency department with non‑traumatic upper gastrointestinal bleeding.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hôpital Universitaire Sahloul (other) |
| Locations | 1 site (Sousse) |
| Trial ID | NCT07089277 on ClinicalTrials.gov |
What this trial studies
This multicenter observational study will enroll adults (≥18 years) presenting with non‑traumatic upper gastrointestinal bleeding to participating emergency departments, with clinical and epidemiological data collected using a standardized form. Investigators will calculate each patient's Glasgow‑Blatchford Score at presentation and follow patients for 30 days to record outcomes including rebleeding, need for hemostatic intervention, complications, and mortality. Statistical analysis will measure the score's predictive performance using sensitivity, specificity, and predictive values for 30‑day outcomes. The goal is to determine whether the GBS can reliably stratify risk in the Tunisian setting where routine hospitalization of all patients is common.
Who should consider this trial
Good fit: Adults (≥18 years) presenting to participating Tunisian emergency departments with non‑traumatic upper gastrointestinal bleeding who consent and have complete follow‑up data.
Not a fit: Patients under 18, those with traumatic or non‑upper GI bleeding (for example isolated hemorrhoidal bleeding), or those who do not consent or are lost to follow‑up are unlikely to benefit.
Why it matters
Potential benefit: If successful, the GBS could help clinicians identify low‑risk patients who may avoid unnecessary hospitalization and allow resources to be focused on higher‑risk individuals.
How similar studies have performed: The Glasgow‑Blatchford Score has demonstrated predictive utility in multiple international cohorts, although validation data specific to Tunisia are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients (≥18 years) presenting with non-traumatic upper gastrointestinal bleeding Exclusion Criteria: * patients under 18 years of age. Diagnosis of external hemorrhoids with mucosal lesions. Patients who do not consent, are lost to follow-up, or have incomplete data.
Where this trial is running
Sousse
- Sahloul University Hospital — Sousse, Tunisia (RECRUITING)
Study contacts
- Study coordinator: Riadh Boukef, Professor
- Email: boukef.riadh@famso.u-sousse.tn
- Phone: +21698676745
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Upper Gastrointestinal Bleeding, Glasgow-Blatchford Score