Testing sleep and wake-promoting techniques for better alertness

Sleep and Wake Countermeasures for Artemis: In-laboratory Study

Not applicable Interventional National Aeronautics and Space Administration (NASA) · NCT06531733

This study is testing if using pink noise and special blue light can help healthy people sleep better and feel more alert during the day.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorNational Aeronautics and Space Administration (NASA) Federal
Locations1 site (Mountain View, California)
Trial IDNCT06531733 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of sleep and wake-promoting countermeasures, specifically pink noise and blue-enriched lighting, to improve sleep quality and alertness in healthy individuals. Participants will undergo two laboratory visits, separated by at least one week, and will maintain a regular sleep schedule at home for 2-3 weeks prior to these visits. The study aims to determine if pink noise can enhance sleep outcomes and if combining it with blue-enriched lighting and napping can further improve alertness and performance. Various assessments will be conducted to measure sleep quality and alertness levels.

Who should consider this trial

Good fit: Ideal candidates are healthy individuals aged 18 to 60 who are pre-menopausal and at least six months postpartum.

Not a fit: Patients with a BMI over 30, sleep disorders, or chronic conditions affecting sleep may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide effective strategies for improving sleep quality and alertness, benefiting individuals who struggle with fatigue.

How similar studies have performed: Other studies have shown promise in using sound and light interventions to improve sleep and alertness, making this approach both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Healthy individuals between the ages of 18 and 60

Individuals who are pre-menopausal must be at least six months post-partum, not breastfeeding, and not planning a pregnancy in the immediate future.

Exclusion Criteria:

BMI \> 30

A sleep disorder of any kind

A chronic condition that could influence sleep (e.g., mood disorders, eye disorders)

A chronic condition that would interfere with data collection and/or potentially make sleep deprivation unsafe (e.g., cardiovascular disorders, diabetes, cancer)

Sensitive skin that would make electrode application intolerable

Use of medication that interferes with sleep (e.g., anti-anxiety, antihistamines, antidepressants, beta blockers)

Travel out of the time zone or stayed up all night in the past month

Individuals who are pregnant.

Individuals with a history of serious chronic conditions or mental illness. It is not possible to list all chronic conditions that may be exclusionary due to the number of medical conditions that would cause an individual to be ineligible. In brief, history of heart failure/disease, cancer, diabetes, seizures, respiratory diseases, sleep disorders, and Lupus are examples of conditions that would be considered exclusionary.

Individuals who test positive for caffeine, alcohol, nicotine, amphetamines, barbiturates, benzodiazepines, cocaine, marijuana, MDMA (ecstasy), methadone, methamphetamines, opiates, oxycodones.

Where this trial is running

Mountain View, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Fatigue
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.