Testing muscle metabolism through exercise
Official title: Exercise Testing in Metabolic Myopathies
Run by University Hospital, Brest · NCT02362685 · Data updated 2026-11-12
This study is testing how exercise affects muscle metabolism in people who might have metabolic muscle disorders to help improve diagnosis and treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 5 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | University Hospital, Brest Academic / other |
| Locations | 1 site (Brest) |
| Status | Recruiting |
| Started | September 2008 |
| Main results expected | December 2027 |
| Study ends | December 2027 |
| Registry record updated | January 22, 2020 |
| Trial ID | NCT02362685 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals referred for a metabolic exercise test at the Physiology Department of Brest Hospital who can provide informed consent.
✕Probably not a fit
Patients with contraindications to cardiopulmonary exercise testing or those who are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the relationship between exercise testing and the results from muscle biopsy or genetic analysis in patients suspected of having metabolic myopathies. By conducting functional tests, the study seeks to measure the concentration of muscle metabolites in the blood during and after exercise. The findings will help to better understand the exertional symptoms associated with these conditions and may aid in diagnosis and treatment planning.
Why it matters
Potential benefit: If successful, this study could improve diagnostic accuracy and treatment strategies for patients with metabolic myopathies.
How similar studies have gone: While this approach is based on established concepts, the specific combination of exercise testing with genetic and biopsy data in this context may be novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Referred to the Physiology Department of Brest Hospital for a metabolic exercise test * Ability to provide informed consent Exclusion Criteria: * Contraindication(s) to perform cardiopulmonary exercise testing (ATS/ACCP statement on cardiopulmonary exercise testing, Am J respi Care Med 167: 211-77, 2003) * Pregnancy or unknown pregnancy status.
Where it's running
-
Centre Hospitalier Régional Universitaire
Brest, France Recruiting
Study contacts
- Principal investigator: Fabrice Rannou, MD, PhD — Chru Brest
- Study coordinator: Fabrice Rannou, MD, PhD
- Email: fabrice.rannou@chu-brest.fr
- Phone: 33(0)298347366
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.