Testing Microtox for Improving Facial Skin Quality and Wrinkles
Effects of PrabotulinumtoxinA-xvfs on Facial Skin Quality, Fine Wrinkles, and Texture
This study is testing if a new treatment called microtox can improve facial skin quality and reduce wrinkles in people looking to enhance their appearance.
Quick facts
| Phase | Phase 1 |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | Female |
| Sponsor | K. Kay Durairaj, MD, FACS, A Medical Corporation Academic / other |
| Locations | 1 site (Pasadena, California) |
| Trial ID | NCT06604832 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of microtox in enhancing facial skin quality, reducing fine wrinkles, and improving skin texture. Participants will be randomly assigned to receive either a neuromodulator treatment on one side of their forehead and a placebo on the other, or a different neuromodulator as a comparator. The study involves one treatment session followed by two assessment visits, where photographs will be taken to track changes over time. A total of 20 subjects will be enrolled, and their progress will be monitored through detailed photographic documentation.
Who should consider this trial
Good fit: Ideal candidates are biological females aged 18-65 with mild to moderate facial wrinkles.
Not a fit: Patients who are pregnant, breastfeeding, or have significant dermatological conditions affecting the face may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide patients with a minimally invasive option to improve the appearance of aging skin.
How similar studies have performed: While similar approaches have been explored, this specific application of microtox is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Biological females, 18-65 years old, of any race and ethnic background * Individuals with mild to moderate facial wrinkles * All skin types (Fitzpatrick I-VI) * Willingness to participate and provide written informed consent * Ability to follow study instructions and likely to complete all required visits Exclusion Criteria: * Females who are pregnant, breastfeeding, chronically using nonsteroidal anti-inflammatory drugs, have autoimmune conditions or have a known allergy to the study medications. * Previous cosmetic procedures near the forehead within the last 6 months or botulinum toxin treatments within the last 4 months * Known neuromuscular disorders or a hypersensitivity to botulinum toxin * Significant dermatological conditions affecting the face * Use of medications affecting neuromuscular function or skin healing within 2 weeks prior to the beginning of study * Subject has a condition or is in a situation which, in the opinion of the Investigator, may put the subject at significant risk, may confound the study results, or may interfere significantly with participation in the study.
Where this trial is running
Pasadena, California
- K. Kay Durairaj, MD, A Medical Corp. — Pasadena, California, United States (Recruiting)
Study contacts
- Principal investigator: Kalpna K Durairaj, MD — K. Kay Durairaj, MD, A Medical Corp.
- Study coordinator: Kalpna K Durairaj, MD
- Email: drkay@beautybydrkay.com
- Phone: 6263167033
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.