Testing health warning labels on e-cigarettes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to develop and test pictorial health warning labels (HWLs) for electronic nicotine delivery systems (ENDS) to assess their impact on young adult users. The study will utilize a clinical lab model to evaluate both subjective outcomes, such as satisfaction and intention to quit, and objective measures, including plasma nicotine levels. The research will involve a systematic approach, starting with literature review and expert feedback to create candidate HWLs, followed by focus groups with young ENDS users to refine these labels. Ultimately, the study seeks to understand how these labels can influence perceptions and behaviors related to ENDS use among young adults.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Generally healthy individuals (determined by physical examination).
* Age of 21-35 years.
* Is willing to provide informed consent.
* Is willing to attend the lab as required by the study protocol.
* ENDS users (defined as using ENDS either daily or occasionally in the past 30 days)
* Have abstained from ENDS use for 12 hours prior to each session.

Exclusion Criteria:

* Report smoking cigarettes regularly (\> 5 cigarettes/month in the past year).
* Report regular use of any other tobacco/nicotine product (e.g., e-cig, pipes, cigars) in the past year.
* Women who are breast-feeding or test positive for pregnancy (by urinalysis at screening).
* Individuals with self-reported history of chronic disease or psychiatric conditions.
* Individuals with history of or active cardiovascular disease, low or high blood pressure, seizures, and regular use of prescription medications (other than vitamins or birth control).
* Individuals that report the use of non-commercial (i.e., street) e-cigarette liquid or products
* Individuals that report current EVALI or COVID-19 related symptoms (i.e., cough, shortness of breath, chest pain, nausea, vomiting, abdominal pain, diarrhea, fever, chills, or weight loss)
* Individuals that have or have been exposed to COVID-19 in the last 14 days.

Where it's running

• Florida International University
  Miami, Florida, United States Recruiting

Study contacts

• Principal investigator: Wasim Maziak, MD, PhD — Florida International University
• Study coordinator: Wasim Maziak, MD, PhD
• Email: wmaziak@fiu.edu
• Phone: 305-348-4501

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Effects of e-cigarette use on health

  This study is trying to see how using e-cigarettes affects heart and lung health over time in people who use them compared to those who don’t.

  Recruiting University of Wisconsin, Madison · Madison, Wisconsin · NCT06610838

• Impact of THC on E-Cigarette Use Behavior

  This study is testing how different doses of THC affect daily e-cigarette users' cravings and use behavior.

  Recruiting Phase 1 Johns Hopkins University · Baltimore, Maryland · NCT06609109

• Investigating how inflammation affects blood vessel health in e-cigarette users

  This study is testing how inflammation affects blood vessel health in young adults who use e-cigarettes compared to those who don’t, while also seeing if an anti-inflammatory medication can help improve their vascular function.

  Recruiting at 2 sites Early Phase 1 University of Iowa · Iowa City, Iowa and 1 other locations · NCT06489249

• Helping dual users of cigarettes and e-cigarettes quit smoking

  This study is testing different ways to help people who smoke both cigarettes and e-cigarettes quit for good by using medications and counseling.

  Recruiting Phase 4 University of Wisconsin, Madison · Madison, Wisconsin · NCT06474299

• Assessing lung and heart effects of vaping in adults

  This study is testing how vaping affects the lungs and heart in adults who use e-cigarettes over five years.

  Recruiting Laval University · Québec · NCT06291597

• Impact of Menthol on E-Cigarette Users' Addiction and Exposure

  This study is testing how menthol-flavored e-cigarettes affect addiction and exposure to harmful substances in young adults aged 21-35.

  Recruiting Florida International University · Miami, Florida · NCT05338801

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.