Testing blood and rectal samples for drug-resistant bacterial infections
Molecular Diagnostics of Bacterial Infections and Antibiotic Resistance in Blood Samples and Rectal Swabs Using Real Time PCR-ARES PCR Methods
NA · IRCCS Sacro Cuore Don Calabria di Negrar · NCT06308692
This study is testing a new way to quickly find drug-resistant bacteria in blood and rectal samples to help improve diagnosis for infections caused by these tough germs.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Sex | All |
| Sponsor | IRCCS Sacro Cuore Don Calabria di Negrar (other) |
| Locations | 1 site (Negrar, Verona) |
| Trial ID | NCT06308692 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of real-time PCR methods to identify drug-resistant bacteria in blood samples and rectal swabs. It utilizes pseudo-anonymized samples archived at the Tropica Biobank, focusing on specific bacterial targets associated with antibiotic resistance. The study aims to improve diagnostic accuracy for infections caused by multi-drug resistant organisms by analyzing data from routine diagnostics at the DITM.
Who should consider this trial
Good fit: Ideal candidates include patients whose blood cultures and multi-drug resistant surveillance tests have been conducted at the IRCCS Sacro Cuore Don Calabria Hospital.
Not a fit: Patients without available data on the presence of targeted bacteria or those who have not consented to the use of their biological samples will not benefit from this study.
Why it matters
Potential benefit: If successful, this could lead to more accurate and timely identification of drug-resistant infections, improving patient outcomes.
How similar studies have performed: Other studies utilizing real-time PCR for diagnosing bacterial infections have shown promising results, indicating that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * Samples of patients for whom blood culture and Multi Drug Resistant (MDR) surveillance tests were carried out in rectal swabs at the IRCCS Sacro Cuore Don Calabria Hospital * Samples for which the Information and consent to the conservation of biological samples for research purposes at the Tropica Biobank has been signed Exclusion criteria: * Absence of data relating to positivity or negativity to the germs of interest * Absence of stored residual material * Absence of information and consent to the conservation of biological samples for signed research purposes
Where this trial is running
Negrar, Verona
- IRCCS Sacro Cuore Don Calabria hospital — Negrar, Verona, Italy (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Drug Resistant Bacterial Infection