Testing an AI model for detecting lymph node metastasis in prostate cancer
Prospective Validation of Pathology-based Artificial Intelligence Diagnostic Model for Lymph Node Metastasis in Prostate Cancer
This study is testing a new AI tool to see if it can better detect cancer spread in lymph nodes for men with prostate cancer compared to standard methods.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Sex | Male |
| Sponsor | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT06253065 on ClinicalTrials.gov |
What this trial studies
This study aims to validate an artificial intelligence diagnostic model designed to detect lymph node metastasis in prostate cancer. The model, developed using deep learning algorithms, will be tested against traditional pathological evaluations to assess its diagnostic performance. Pathological slides from patients undergoing radical prostatectomy will be digitized into whole-slide images for analysis by the AI model, which will generate diagnostic results and heatmaps. The study seeks to determine if the AI can enhance the accuracy and efficiency of lymph node evaluations in clinical practice.
Who should consider this trial
Good fit: Ideal candidates are patients with prostate cancer who are scheduled for radical prostatectomy and pelvic lymph node dissection.
Not a fit: Patients with other tumors that have metastasized to pelvic lymph nodes will not benefit from this study.
Why it matters
Potential benefit: If successful, this AI model could significantly improve the accuracy of lymph node metastasis detection in prostate cancer, leading to better treatment decisions.
How similar studies have performed: Previous studies have shown promise in using AI for diagnostic purposes in pathology, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with prostate cancer, undergoing radical prostatectomy and pelvic lymph node dissection. * Patients with complete clinical and pathological information. Exclusion Criteria: * Patients with other tumors that metastasized to pelvic lymph nodes. * The patient refused to participate in this diagnostic test.
Where this trial is running
Guangzhou, Guangdong
- Sun Yat-sen Memorial Hospital of Sun Yat-sen University — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: Tianxin Lin, Ph.D
- Email: lintx@mail.sysu.edu.cn
- Phone: 13724008338, China
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.